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Periocular Basal Cell Carcinoma: 20-Years Experience at a Tertiary Eye Care Center of South India
PURPOSE: To study the clinical profile and management outcomes of periocular basal cell carcinoma (BCC). MATERIALS AND METHODS: A retrospective analysis of all histopathologically proven cases of BCC between 1995 and 2015 was done. The demographic data, clinical presentation, histopathological subty...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852420/ https://www.ncbi.nlm.nih.gov/pubmed/33542600 http://dx.doi.org/10.4103/ojo.OJO_130_2019 |
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author | Vijay, Vathsalya Alam, Md. Shahid Subramanian, Nirmala Krishnakumar, Subramanian Biswas, Jyotirmay Mukherjee, Bipasha |
author_facet | Vijay, Vathsalya Alam, Md. Shahid Subramanian, Nirmala Krishnakumar, Subramanian Biswas, Jyotirmay Mukherjee, Bipasha |
author_sort | Vijay, Vathsalya |
collection | PubMed |
description | PURPOSE: To study the clinical profile and management outcomes of periocular basal cell carcinoma (BCC). MATERIALS AND METHODS: A retrospective analysis of all histopathologically proven cases of BCC between 1995 and 2015 was done. The demographic data, clinical presentation, histopathological subtype, and management outcomes were analyzed. RESULTS: We had a total of 185 malignant eyelid tumors during the study period, out of which 37 (20%) were BCC. Thirty-two (86.5%) out of 37 cases were primary BCC. The mean age was 63.3 years. Pigmented ulcerative lesion (14, 38%), lower eyelid (19, 51%), and nodular BCC (15, 40%) were the most common presentation, periocular site, and histological subtype, respectively. 28 patients underwent excision under frozen section with an average tumor-free margin of 3.5 mm. Mean follow-up period was 18.78 months. Recurrence rate of 0% and 3.1% was noted in primary and recurrent BCC, respectively. CONCLUSION: Periocular BCC commonly presents as pigmented ulcerative lesion in the lower lid. Excision biopsy under frozen section with an average tumor-free margin of 3.5 mm offers cure in most cases. |
format | Online Article Text |
id | pubmed-7852420 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-78524202021-02-03 Periocular Basal Cell Carcinoma: 20-Years Experience at a Tertiary Eye Care Center of South India Vijay, Vathsalya Alam, Md. Shahid Subramanian, Nirmala Krishnakumar, Subramanian Biswas, Jyotirmay Mukherjee, Bipasha Oman J Ophthalmol Original Article PURPOSE: To study the clinical profile and management outcomes of periocular basal cell carcinoma (BCC). MATERIALS AND METHODS: A retrospective analysis of all histopathologically proven cases of BCC between 1995 and 2015 was done. The demographic data, clinical presentation, histopathological subtype, and management outcomes were analyzed. RESULTS: We had a total of 185 malignant eyelid tumors during the study period, out of which 37 (20%) were BCC. Thirty-two (86.5%) out of 37 cases were primary BCC. The mean age was 63.3 years. Pigmented ulcerative lesion (14, 38%), lower eyelid (19, 51%), and nodular BCC (15, 40%) were the most common presentation, periocular site, and histological subtype, respectively. 28 patients underwent excision under frozen section with an average tumor-free margin of 3.5 mm. Mean follow-up period was 18.78 months. Recurrence rate of 0% and 3.1% was noted in primary and recurrent BCC, respectively. CONCLUSION: Periocular BCC commonly presents as pigmented ulcerative lesion in the lower lid. Excision biopsy under frozen section with an average tumor-free margin of 3.5 mm offers cure in most cases. Wolters Kluwer - Medknow 2020-11-02 /pmc/articles/PMC7852420/ /pubmed/33542600 http://dx.doi.org/10.4103/ojo.OJO_130_2019 Text en Copyright: © 2020 Oman Ophthalmic Society http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Vijay, Vathsalya Alam, Md. Shahid Subramanian, Nirmala Krishnakumar, Subramanian Biswas, Jyotirmay Mukherjee, Bipasha Periocular Basal Cell Carcinoma: 20-Years Experience at a Tertiary Eye Care Center of South India |
title | Periocular Basal Cell Carcinoma: 20-Years Experience at a Tertiary Eye Care Center of South India |
title_full | Periocular Basal Cell Carcinoma: 20-Years Experience at a Tertiary Eye Care Center of South India |
title_fullStr | Periocular Basal Cell Carcinoma: 20-Years Experience at a Tertiary Eye Care Center of South India |
title_full_unstemmed | Periocular Basal Cell Carcinoma: 20-Years Experience at a Tertiary Eye Care Center of South India |
title_short | Periocular Basal Cell Carcinoma: 20-Years Experience at a Tertiary Eye Care Center of South India |
title_sort | periocular basal cell carcinoma: 20-years experience at a tertiary eye care center of south india |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852420/ https://www.ncbi.nlm.nih.gov/pubmed/33542600 http://dx.doi.org/10.4103/ojo.OJO_130_2019 |
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