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Class I HDAC Inhibitor Improves Synaptic Proteins and Repairs Cytoskeleton Through Regulating Synapse-Related Genes In vitro and In vivo

β-amyloid (Aβ) is an important protein molecule in the pathology of Alzheimer’s disease (AD). Accumulation of Aβ leads to the loss of dendritic spines and synapses. These impairments can be ameliorated by histone deacetylase inhibitors (HDACI). However, the mechanisms of HDACIs underlying the effect...

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Detalles Bibliográficos
Autores principales:	Han, Ying, Chen, Le, Guo, Yu, Wang, Chunyang, Zhang, Chenghong, Kong, Li, Ma, Haiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852506/ https://www.ncbi.nlm.nih.gov/pubmed/33542682 http://dx.doi.org/10.3389/fnagi.2020.619866

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