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Intranasal delivery of mesenchymal stem cell secretome repairs the brain of Alzheimer’s mice

The multiplicity of systems affected in Alzheimer’s disease (AD) brains calls for multi-target therapies. Although mesenchymal stem cells (MSC) are promising candidates, their clinical application is limited because of risks related to their direct implantation in the host. This could be overcome by...

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Detalles Bibliográficos
Autores principales: Santamaria, Giulia, Brandi, Edoardo, Vitola, Pietro La, Grandi, Federica, Ferrara, Giovanni, Pischiutta, Francesca, Vegliante, Gloria, Zanier, Elisa R., Re, Francesca, Uccelli, Antonio, Forloni, Gianluigi, de Rosbo, Nicole Kerlero, Balducci, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852675/
https://www.ncbi.nlm.nih.gov/pubmed/32704089
http://dx.doi.org/10.1038/s41418-020-0592-2