Cargando…
Generation of genetically tailored porcine liver cancer cells by CRISPR/Cas9 editing
Pigs provide a valuable large animal model for several diseases due to their similarity with humans in anatomy, physiology, genetics and drug metabolism. We recently generated a porcine model for TP53(R167H) and KRAS(G12D) driven hepatocellular carcinoma (HCC) by autologous liver implantation. Here...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Future Science Ltd
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852845/ https://www.ncbi.nlm.nih.gov/pubmed/33222517 http://dx.doi.org/10.2144/btn-2020-0119 |