Cargando…

Searching for causal relationships of glioma: a phenome-wide Mendelian randomisation study

BACKGROUND: The aetiology of glioma is poorly understood. Summary data from genome-wide association studies (GWAS) can be used in a Mendelian randomisation (MR) phenome-wide association study (PheWAS) to search for glioma risk factors. METHODS: We performed an MR-PheWAS analysing 316 phenotypes, pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saunders, Charlie N., Cornish, Alex J., Kinnersley, Ben, Law, Philip J., Houlston, Richard S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852872/ https://www.ncbi.nlm.nih.gov/pubmed/33020596 http://dx.doi.org/10.1038/s41416-020-01083-1

Ejemplares similares

Relationship between genetically determined telomere length and glioma risk
por: Saunders, Charlie N, et al.
Publicado: (2021)

Phenome-wide Mendelian randomisation analysis identifies causal factors for age-related macular degeneration
por: Julian, Thomas H, et al.
Publicado: (2023)

Causal factors in primary open angle glaucoma: a phenome-wide Mendelian randomisation study
por: Julian, Thomas H., et al.
Publicado: (2023)

Risk factors for eight common cancers revealed from a phenome-wide Mendelian randomisation analysis of 378,142 cases and 485,715 controls
por: Went, Molly, et al.
Publicado: (2023)

Risk factors for eight common cancers revealed from a phenome-wide Mendelian randomisation analysis of 378,142 cases and 485,715 controls
por: Went, Molly, et al.
Publicado: (2023)

Mendelian randomisation study of the relationship between vitamin D and risk of glioma
por: Takahashi, Hannah, et al.
Publicado: (2018)

Lack of association between modifiable exposures and glioma risk: a Mendelian randomization analysis
por: Saunders, Charlie N, et al.
Publicado: (2020)

Publisher Correction: Mendelian randomisation study of the relationship between vitamin D and risk of glioma
por: Takahashi, Hannah, et al.
Publicado: (2019)

Impact of atopy on risk of glioma: a Mendelian randomisation study
por: Disney-Hogg, Linden, et al.
Publicado: (2018)

The Causal Relationships Between Extrinsic Exposures and Risk of Prostate Cancer: A Phenome-Wide Mendelian Randomization Study
por: Gu, Dongqing, et al.
Publicado: (2022)

Identifying potential causal effects of age at menarche: a Mendelian randomization phenome-wide association study
por: Magnus, Maria C., et al.
Publicado: (2020)

Identifying potential causal effects of age at menopause: a Mendelian randomization phenome-wide association study
por: Magnus, Maria C., et al.
Publicado: (2022)

Health effects of high serum calcium levels: Updated phenome-wide Mendelian randomisation investigation and review of Mendelian randomisation studies
por: Yuan, Shuai, et al.
Publicado: (2022)

Cancer drivers and clonal dynamics in acute lymphoblastic leukaemia subtypes
por: Studd, James B., et al.
Publicado: (2021)

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
por: Shen, Xueyi, et al.
Publicado: (2020)

Identifying the potential causal role of insomnia symptoms on 11,409 health-related outcomes: a phenome-wide Mendelian randomisation analysis in UK Biobank
por: Gibson, Mark J., et al.
Publicado: (2023)

The Causal Association of Irritable Bowel Syndrome with Multiple Disease Outcomes: A Phenome-Wide Mendelian Randomization Study
por: Li, Chunyang, et al.
Publicado: (2023)

Mendelian randomisation: A powerful and inexpensive method for identifying and excluding non-genetic risk factors for colorectal cancer
por: Cornish, Alex J., et al.
Publicado: (2019)

The Causal Effects of Blood Iron and Copper on Lipid Metabolism Diseases: Evidence from Phenome-Wide Mendelian Randomization Study
por: Zhou, Jingqi, et al.
Publicado: (2020)

The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomization
por: Korologou-Linden, Roxanna, et al.
Publicado: (2022)

A phenome-wide bidirectional Mendelian randomization analysis of atrial fibrillation
por: Wang, Qin, et al.
Publicado: (2022)

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
por: Zheng, Jie, et al.
Publicado: (2020)

Exploring the causal role of the immune response to varicella-zoster virus on multiple traits: a phenome-wide Mendelian randomization study
por: Yu, Xinzhu, et al.
Publicado: (2023)

Health effects of milk consumption: phenome-wide Mendelian randomization study
por: Yuan, Shuai, et al.
Publicado: (2022)

Phenome-wide investigation of the causal associations between childhood BMI and adult trait outcomes: a two-sample Mendelian randomization study
por: Dong, Shan-Shan, et al.
Publicado: (2021)

Phenome-wide Mendelian randomization study of plasma triglyceride levels and 2600 disease traits
por: Park, Joshua K, et al.
Publicado: (2023)

Modifiable pathways for colorectal cancer: a mendelian randomisation analysis
por: Cornish, Alex J, et al.
Publicado: (2019)

Causal relationships between risk of venous thromboembolism and 18 cancers: a bidirectional Mendelian randomisation analysis
por: Cornish, Naomi, et al.
Publicado: (2023)

A phenome-wide approach to identify causal risk factors for deep vein thrombosis
por: Constantinescu, Andrei-Emil, et al.
Publicado: (2023)

Graphical analysis for phenome-wide causal discovery in genotyped population-scale biobanks
por: Amar, David, et al.
Publicado: (2021)

Mendelian Randomisation and Causal Inference in Observational Epidemiology
por: Sheehan, Nuala A, et al.
Publicado: (2008)

Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank
por: Zhang, Xiaomeng, et al.
Publicado: (2021)

Associations of genetically predicted fatty acid levels across the phenome: A mendelian randomisation study
por: Zagkos, Loukas, et al.
Publicado: (2022)

Genetically predicted sex hormone levels and health outcomes: phenome-wide Mendelian randomization investigation
por: Yuan, Shuai, et al.
Publicado: (2022)

Phenome-wide Mendelian randomization study evaluating the association of circulating vitamin D with complex diseases
por: Xu, Jin-jian, et al.
Publicado: (2023)

Education and myopia: assessing the direction of causality by mendelian randomisation
Publicado: (2018)

Education and myopia: assessing the direction of causality by mendelian randomisation
por: Mountjoy, Edward, et al.
Publicado: (2018)

Phenome-wide analysis highlights putative causal relationships between self-reported migraine and other complex traits
por: García-Marín, Luis M., et al.
Publicado: (2021)

Lack of an association between gallstone disease and bilirubin levels with risk of colorectal cancer: a Mendelian randomisation analysis
por: Culliford, Richard, et al.
Publicado: (2021)

PHENOME-WIDE SEARCH OF COGNITIVE RESERVE PROXIES ACROSS AGE COHORTS
por: Zheng, Anqing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1v445a5bujgg1l1akb2gfnr4gu