RIP3-mediated necroptosis is regulated by inter-filament assembly of RIP homotypic interaction motif

Necroptosis is mediated by signaling complexes called necrosomes, which contain receptor-interacting protein 3 (RIP3) and upstream effectors, such as RIP1. In necrosomes, the RIP homotypic interaction motif (RHIM) of RIP3 and RIP1 forms amyloidal complex. But how the amyloidal necrosomes control RIP...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Hong, Wu, Xialian, Wu, Guoxiang, Nan, Ning, Zhang, Jing, Zhu, Xinxin, Zhang, Yu, Shu, Zhaoqian, Liu, Jia, Liu, Xiaoyan, Lu, Junxia, Wang, Huayi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853141/
https://www.ncbi.nlm.nih.gov/pubmed/32737444
http://dx.doi.org/10.1038/s41418-020-0598-9

Ejemplares similares

Ejemplares similares