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Systematic Design and Validation of Ion Channel Stabilization of Amphipathic α-Helical Peptides Incorporating Tryptophan Residues

[Image: see text] Aromatic interactions such as π–π interaction and cation−π interaction are present in membrane proteins and play important roles in both structure and function. To systematically investigate the effect of aromatic residues on the structural stability and ion permeability of peptide...

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Detalles Bibliográficos
Autores principales:	Shigedomi, Keita, Osada, Satoshi, Jelokhani-Niaraki, Masoud, Kodama, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853622/ https://www.ncbi.nlm.nih.gov/pubmed/33553860 http://dx.doi.org/10.1021/acsomega.0c05254

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