Cargando…

Vinpocetine Attenuates Ischemic Stroke Through Inhibiting NLRP3 Inflammasome Expression in Mice

Ischemic stroke is the leading cause of globe death and permanent disability, but its therapeutic strategies are limited. Over the past decades, multiprotein complexes called inflammasomes have been shown as promising targets in ischemic stroke. Here, we examined vinpocetine (Vinp), a synthetic drug...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Dong, Wang, Jue, Wen, Lulu, Sun, Miao, Liu, Hang, Gao, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Journal of Cardiovascular Pharmacology 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853762/ https://www.ncbi.nlm.nih.gov/pubmed/33351536 http://dx.doi.org/10.1097/FJC.0000000000000945

Ejemplares similares

Role of vinpocetine in ischemic stroke and poststroke outcomes: A critical review
por: Al-Kuraishy, Hayder M., et al.
Publicado: (2020)

Remote Limb Ischemic Postconditioning Protects against Ischemic Stroke via Modulating Microglia/Macrophage Polarization in Mice
por: Han, Dong, et al.
Publicado: (2021)

Inhibition of NLRP3 Inflammasome: A Prospective Target for the Treatment of Ischemic Stroke
por: Feng, Ya-Shuo, et al.
Publicado: (2020)

Genistein Attenuates Acute Cerebral Ischemic Damage by Inhibiting the NLRP3 Inflammasome in Reproductively Senescent Mice
por: Wang, Shiquan, et al.
Publicado: (2020)

Anti-Inflammatory Effects of Vinpocetine in Atherosclerosis and Ischemic Stroke: A Review of the Literature
por: Zhang, Linjie, et al.
Publicado: (2014)

Inhibition of PDE1-B by Vinpocetine Regulates Microglial Exosomes and Polarization Through Enhancing Autophagic Flux for Neuroprotection Against Ischemic Stroke
por: Zang, Jiankun, et al.
Publicado: (2021)

Electroacupuncture attenuated cerebral ischemic injury and neuroinflammation through α7nAChR-mediated inhibition of NLRP3 inflammasome in stroke rats
por: Jiang, Tao, et al.
Publicado: (2019)

Hydrogen-Rich Saline Inhibits NLRP3 Inflammasome Activation and Attenuates Experimental Acute Pancreatitis in Mice
por: Ren, Jian-Dong, et al.
Publicado: (2014)

NLRP3 inflammasome as a potential treatment in ischemic stroke concomitant with diabetes
por: Hong, Pu, et al.
Publicado: (2019)

Oleanolic Acid Provides Neuroprotection against Ischemic Stroke through the Inhibition of Microglial Activation and NLRP3 Inflammasome Activation
por: Sapkota, Arjun, et al.
Publicado: (2022)

Delayed NLRP3 inflammasome inhibition ameliorates subacute stroke progression in mice
por: Bellut, Maximilian, et al.
Publicado: (2023)

Pharmacological intervention of curcumin via the NLRP3 inflammasome in ischemic stroke
por: Du, Xiaoxue, et al.
Publicado: (2023)

Vinpocetine Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells
por: Ma, Yun-Yun, et al.
Publicado: (2016)

Apigenin attenuates atherosclerosis and non-alcoholic fatty liver disease through inhibition of NLRP3 inflammasome in mice
por: Lu, Zheng, et al.
Publicado: (2023)

Yupingfeng San Inhibits NLRP3 Inflammasome to Attenuate the Inflammatory Response in Asthma Mice
por: Liu, Xue, et al.
Publicado: (2017)

Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation
por: Zhu, Xi, et al.
Publicado: (2022)

Tanshinone IIA attenuates atherosclerosis via inhibiting NLRP3 inflammasome activation
por: Wen, Jiexia, et al.
Publicado: (2020)

Naoxintong attenuates Ischaemia/reperfusion Injury through inhibiting NLRP3 inflammasome activation
por: Wang, Yaqiong, et al.
Publicado: (2016)

Isoquercitrin Attenuates Steatohepatitis by Inhibition of the Activated NLRP3 Inflammasome through HSP90
por: Ma, Ji, et al.
Publicado: (2023)

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke
por: Yang-Wei Fann, D, et al.
Publicado: (2013)

Ischemic Preconditioning Provides Neuroprotection by Inhibiting NLRP3 Inflammasome Activation and Cell Pyroptosis
por: Gao, Li, et al.
Publicado: (2023)

Attenuated effects of topical vinpocetine in an imiquimod-induced mouse model of psoriasis
por: Salman, Hayder R., et al.
Publicado: (2023)

Safety and Efficacy of Vinpocetine as a Neuroprotective Agent in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis
por: Panda, Prateek Kumar, et al.
Publicado: (2022)

Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice
por: Jiang, Wu, et al.
Publicado: (2017)

Vinpocetine Attenuates Neointimal Hyperplasia in Diabetic Rat Carotid Arteries after Balloon Injury
por: Wang, Ke, et al.
Publicado: (2014)

Inhibiting the NLRP3 Inflammasome
por: El-Sharkawy, Lina Y., et al.
Publicado: (2020)

Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF-κB Suppression and NLRP3 Inflammasome Inhibition
por: Ran, Yuanyuan, et al.
Publicado: (2021)

Melatonin Attenuates Spinal Cord Injury in Mice by Activating the Nrf2/ARE Signaling Pathway to Inhibit the NLRP3 Inflammasome
por: Wang, Haoyu, et al.
Publicado: (2022)

Itaconate Attenuates Neuroinflammation and Exerts Dopamine Neuroprotection in Parkinson’s Disease through Inhibiting NLRP3 Inflammasome
por: Sun, Guoqing, et al.
Publicado: (2022)

Focus on the role of mitochondria in NLRP3 inflammasome activation: A prospective target for the treatment of ischemic stroke (Review)
por: Zhang, Xiaolu, et al.
Publicado: (2022)

Fisetin Attenuates Diabetic Nephropathy-Induced Podocyte Injury by Inhibiting NLRP3 Inflammasome
por: Dong, Wenmin, et al.
Publicado: (2022)

Oridonin ameliorates carbon tetrachloride‐induced liver fibrosis in mice through inhibition of the NLRP3 inflammasome
por: Liu, Dong, et al.
Publicado: (2020)

Inhibition of the Inflammasome Activity of NLRP3 Attenuates HDM-Induced Allergic Asthma
por: Ma, Ming, et al.
Publicado: (2021)

Gemigliptin Attenuates Renal Fibrosis Through Down-Regulation of the NLRP3 Inflammasome
por: Seo, Jung Beom, et al.
Publicado: (2019)

The role of NLRP3 inflammasome-mediated pyroptosis in ischemic stroke and the intervention of traditional Chinese medicine
por: Long, Jia-Xin, et al.
Publicado: (2023)

Blockage of P2X7 attenuates acute lung injury in mice by inhibiting NLRP3 inflammasome
por: Wang, Shuang, et al.
Publicado: (2015)

Janus Kinase Inhibition Ameliorates Ischemic Stroke Injury and Neuroinflammation Through Reducing NLRP3 Inflammasome Activation via JAK2/STAT3 Pathway Inhibition
por: Zhu, Hua, et al.
Publicado: (2021)

NLRP3 inflammasome in rosmarinic acid-afforded attenuation of acute kidney injury in mice
por: Akhter, Juheb, et al.
Publicado: (2022)

Inhibition of the NLRP3-inflammasome as a potential approach for neuroprotection after stroke
por: Ismael, Saifudeen, et al.
Publicado: (2018)

TMAO Promotes NLRP3 Inflammasome Activation of Microglia Aggravating Neurological Injury in Ischemic Stroke Through FTO/IGF2BP2
por: Ge, Pengxin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ung3ijb14hribg8tserdvj92pj