Impact of Implementing CYP2C19 Genotype-Guided Antiplatelet Therapy on P2Y(12) Inhibitor Selection and Clinical Outcomes in Acute Coronary Syndrome Patients After Percutaneous Coronary Intervention: A Real-World Study in China

Background: CYP2C19 loss-of-function (LOF) alleles reduce the effectiveness of clopidogrel in patients undergoing percutaneous coronary intervention for acute coronary syndrome. However, the clinical impact of implementing CYP2C19 gene-guided pharmacotherapy is unclear, especially among the Chinese...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Shi, Xiu-Jin, Peng, Wen-Xing, Han, Jia-Lun, Lin, Bai-Di, Zhang, Ru, Zhang, Yun-Nan, Yan, Jia-Lin, Wei, Juan-Juan, Wang, Yi-Fan, Chen, Su-Wei, Nan, Nan, Fang, Zhen-Wei, Zeng, Yong, Lin, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854467/
https://www.ncbi.nlm.nih.gov/pubmed/33551797
http://dx.doi.org/10.3389/fphar.2020.582929

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