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Maternal Immune Activation in Mice Disrupts Proteostasis in the Fetal Brain

Maternal infection and inflammation during pregnancy are associated with neurodevelopmental disorders in offspring, but little is understood about the molecular mechanisms underlying this epidemiologic phenomenon. We leveraged single-cell RNA sequencing to profile transcriptional changes in the mous...

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Detalles Bibliográficos
Autores principales: Kalish, Brian T., Kim, Eunha, Finander, Benjamin, Duffy, Erin E., Kim, Hyunju, Gilman, Casey K., Yim, Yeong Shin, Tong, Lilin, Kaufman, Randal J., Griffith, Eric C., Choi, Gloria B., Greenberg, Michael E., Huh, Jun R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854524/
https://www.ncbi.nlm.nih.gov/pubmed/33361822
http://dx.doi.org/10.1038/s41593-020-00762-9