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Drug-Resistant Temporal Lobe Epilepsy Alters the Expression and Functional Coupling to Gαi/o Proteins of CB1 and CB2 Receptors in the Microvasculature of the Human Brain

Cannabinoid receptors 1 and 2 (CB1 and CB2, respectively) play an important role in maintaining the integrity of the blood–brain barrier (BBB). On the other hand, BBB dysfunction is a common feature in drug-resistant epilepsy. The focus of the present study was to characterize protein expression lev...

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Detalles Bibliográficos
Autores principales: Nuñez-Lumbreras, María de los Ángeles, Castañeda-Cabral, José Luis, Valle-Dorado, María Guadalupe, Sánchez-Valle, Vicente, Orozco-Suárez, Sandra, Guevara-Guzmán, Rosalinda, Martínez-Juárez, Iris, Alonso-Vanegas, Mario, Walter, Fruzsina, Deli, Maria A., Carmona-Cruz, Francia, Rocha, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854549/
https://www.ncbi.nlm.nih.gov/pubmed/33551765
http://dx.doi.org/10.3389/fnbeh.2020.611780

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