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Structural basis for ligand recognition of the neuropeptide Y Y(2) receptor

The human neuropeptide Y (NPY) Y(2) receptor (Y(2)R) plays essential roles in food intake, bone formation and mood regulation, and has been considered an important drug target for obesity and anxiety. However, development of drugs targeting Y(2)R remains challenging with no success in clinical appli...

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Detalles Bibliográficos
Autores principales: Tang, Tingting, Hartig, Christin, Chen, Qiuru, Zhao, Wenli, Kaiser, Anette, Zhang, Xuefeng, Zhang, Hui, Qu, Honge, Yi, Cuiying, Ma, Limin, Han, Shuo, Zhao, Qiang, Beck-Sickinger, Annette G., Wu, Beili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854658/
https://www.ncbi.nlm.nih.gov/pubmed/33531491
http://dx.doi.org/10.1038/s41467-021-21030-9