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Structural basis for ligand recognition of the neuropeptide Y Y(2) receptor
The human neuropeptide Y (NPY) Y(2) receptor (Y(2)R) plays essential roles in food intake, bone formation and mood regulation, and has been considered an important drug target for obesity and anxiety. However, development of drugs targeting Y(2)R remains challenging with no success in clinical appli...
Autores principales: | Tang, Tingting, Hartig, Christin, Chen, Qiuru, Zhao, Wenli, Kaiser, Anette, Zhang, Xuefeng, Zhang, Hui, Qu, Honge, Yi, Cuiying, Ma, Limin, Han, Shuo, Zhao, Qiang, Beck-Sickinger, Annette G., Wu, Beili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854658/ https://www.ncbi.nlm.nih.gov/pubmed/33531491 http://dx.doi.org/10.1038/s41467-021-21030-9 |
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