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Cross-species single-cell transcriptomic analysis reveals pre-gastrulation developmental differences among pigs, monkeys, and humans

Interspecies blastocyst complementation enables organ-specific enrichment of xenogeneic pluripotent stem cell (PSC) derivatives, which raises an intriguing possibility to generate functional human tissues/organs in an animal host. However, differences in embryo development between human and host spe...

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Detalles Bibliográficos
Autores principales: Liu, Tianbin, Li, Jie, Yu, Leqian, Sun, Hai-Xi, Li, Jing, Dong, Guoyi, Hu, Yingying, Li, Yong, Shen, Yue, Wu, Jun, Gu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854681/
https://www.ncbi.nlm.nih.gov/pubmed/33531465
http://dx.doi.org/10.1038/s41421-020-00238-x

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