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A safety cap protects hydrogenase from oxygen attack

[FeFe]-hydrogenases are efficient H(2)-catalysts, yet upon contact with dioxygen their catalytic cofactor (H-cluster) is irreversibly inactivated. Here, we combine X-ray crystallography, rational protein design, direct electrochemistry, and Fourier-transform infrared spectroscopy to describe a prote...

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Detalles Bibliográficos
Autores principales:	Winkler, Martin, Duan, Jifu, Rutz, Andreas, Felbek, Christina, Scholtysek, Lisa, Lampret, Oliver, Jaenecke, Jan, Apfel, Ulf-Peter, Gilardi, Gianfranco, Valetti, Francesca, Fourmond, Vincent, Hofmann, Eckhard, Léger, Christophe, Happe, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854748/ https://www.ncbi.nlm.nih.gov/pubmed/33531463 http://dx.doi.org/10.1038/s41467-020-20861-2

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