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The Newborn Fmr1 Knockout Mouse: A Novel Model of Excess Ubiquinone and Closed Mitochondrial Permeability Transition Pore in the Developing Heart

BACKGROUND: Mitochondrial permeability transition pore (mPTP) closure triggers cardiomyocyte differentiation during development while pathological opening causes cell death during myocardial ischemia-reperfusion and heart failure. Ubiquinone modulates the mPTP, however, little is known about its mec...

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Detalles Bibliográficos
Autores principales:	Barajas, Matthew, Wang, Aili, Griffiths, Keren K., Matsumoto, Kenji, Liu, Rui, Homma, Shunichi, Levy, Richard J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855053/ https://www.ncbi.nlm.nih.gov/pubmed/32674111 http://dx.doi.org/10.1038/s41390-020-1064-6

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