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Modeling the activity of the dopamine signaling pathway by combination of analog electrical circuit and mathematical approaches
This paper demonstrates the application of the system biology principles on the example of the dopamine signaling pathway in neurons. Presented model is based on two approaches – cytomorphic electronic circuits and mathematical modeling. Transcription and phosphorylation of DARPP-32 was modeled by a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855338/ https://www.ncbi.nlm.nih.gov/pubmed/33553717 http://dx.doi.org/10.1016/j.heliyon.2020.e05879 |