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Mycobacterium tuberculosis-specific CD4 T cells expressing CD153 inversely associate with bacterial load and disease severity in human tuberculosis

Recent data from mice and non-human primate models of tuberculosis suggested that CD153, a TNF super family member, plays an important role in Mycobacterium tuberculosis (Mtb) control. However, this molecule has not been comprehensively evaluated in humans. Here, we show that the proportion of Mtb-s...

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Detalles Bibliográficos
Autores principales:	Du Bruyn, Elsa, Ruzive, Sheena, Lindestam Arlehamn, Cecilia S., Sette, Alessandro, Sher, Alan, Barber, Daniel L., Wilkinson, Robert J., Riou, Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855386/ https://www.ncbi.nlm.nih.gov/pubmed/32678272 http://dx.doi.org/10.1038/s41385-020-0322-6

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