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Co-Inhibition of the Immunoproteasome Subunits LMP2 and LMP7 Ameliorates Immune Thrombocytopenia

The immunoproteasome, a special isoform of the 20S proteasome, is expressed when the cells receive an inflammatory signal. Immunoproteasome inhibition proved efficacy in the treatment of autoimmune diseases. However, the role of the immunoproteasome in the pathogenesis of immune thrombocytopenia (IT...

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Detalles Bibliográficos
Autores principales: Du, Sheng-hong, Xiang, Yu-jiao, Liu, Lu, Nie, Mu, Hou, Yu, Wang, Ling, Li, Ban-ban, Xu, Miao, Teng, Qing-liang, Peng, Jun, Hou, Ming, Shi, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855704/
https://www.ncbi.nlm.nih.gov/pubmed/33552061
http://dx.doi.org/10.3389/fimmu.2020.603278

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