DNA-protein crosslinks are repaired via homologous recombination in mammalian mitochondria

While mammalian mitochondria are known to possess a robust base excision repair system, direct evidence for the existence of additional mitochondrial DNA repair pathways is elusive. Herein a PCR-based assay was employed to demonstrate that plasmids containing DNA-protein crosslinks are rapidly repai...

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Detalles Bibliográficos
Autores principales: Chesner, Lisa N., Essawy, Maram, Warner, Cecilia, Campbell, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855827/
https://www.ncbi.nlm.nih.gov/pubmed/33316746
http://dx.doi.org/10.1016/j.dnarep.2020.103026

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