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Management of Primary Central Nervous System Lymphoma Using Intra-Arterial Chemotherapy With Osmotic Blood-Brain Barrier Disruption: Retrospective Analysis of the Sherbrooke Cohort

BACKGROUND: Primary central nervous system lymphomas (PCNSL) are rare and aggressive CNS tumors. Current management involves high-dose methotrexate (HD-MTX) typically administered intravenously (IV), despite the existence of the blood-brain barrier (BBB), which significantly decreases its bioavailab...

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Detalles Bibliográficos
Autores principales:	Iorio-Morin, Christian, Gahide, Gérald, Morin, Christophe, Vanderweyen, Davy, Roy, Marie-André, St-Pierre, Isabelle, Massicotte-Tisluck, Karine, Fortin, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855856/ https://www.ncbi.nlm.nih.gov/pubmed/33552946 http://dx.doi.org/10.3389/fonc.2020.543648

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