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Genetic and Non-genetic Factors Contributing to the Significant Variation in the Plasma Trough Concentration-to-Dose Ratio of Valproic Acid in Children With Epilepsy

Objective: This study was conducted to evaluate the potential genetic and non-genetic factors contributing to plasma trough concentration-to-dose (C(0)/D) ratio of valproic acid (VPA) in pediatric patients with epilepsy. Study Design: A single-center, retrospective cohort study was performed by coll...

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Detalles Bibliográficos
Autores principales:	Xu, Ze-Yue, Guo, Hong-Li, Li, Ling, Zhang, Min, Jing, Xia, Xu, Ze-Jun, Qiu, Jin-Chun, Lu, Xiao-Peng, Ding, Xuan-Sheng, Chen, Feng, Xu, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pediatrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855978/ https://www.ncbi.nlm.nih.gov/pubmed/33553069 http://dx.doi.org/10.3389/fped.2020.599044

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