Metallaphotoredox Aryl and Alkyl Radiomethylation for PET Ligand Discovery

Positron emission tomography (PET) radioligands are highly enabling tracers which facilitate in vivo characterization of central nervous system (CNS) drug candidates, neurodegenerative diseases, and numerous oncology targets(1). While both tritium and carbon-11 radioisotopologs are generally necessa...

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Detalles Bibliográficos
Autores principales: Pipal, Robert W., Stout, Kenneth T., Musacchio, Patricia Z., Ren, Sumei, Graham, Thomas J. A., Verhoog, Stefan, Gantert, Liza, Lohith, Talakad G., Schmitz, Alexander, Lee, Hsiaoju S., Hesk, David, Hostetler, Eric D., Davies, Ian W., MacMillan, David W. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856055/
https://www.ncbi.nlm.nih.gov/pubmed/33238289
http://dx.doi.org/10.1038/s41586-020-3015-0

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