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The multifaceted role of PARP1 in RNA biogenesis

Poly(ADP‐ribose) polymerases (PARPs) are abundant nuclear proteins that synthesize ADP ribose polymers (pADPr) and catalyze the addition of (p)ADPr to target biomolecules. PARP1, the most abundant and well‐studied PARP, is a multifunctional enzyme that participates in numerous critical cellular proc...

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Detalles Bibliográficos
Autores principales: Eleazer, Rebekah, Fondufe‐Mittendorf, Yvonne N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856298/
https://www.ncbi.nlm.nih.gov/pubmed/32656996
http://dx.doi.org/10.1002/wrna.1617