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CD8+ T-Cell Repertoire in Human Leukocyte Antigen Class I-Mismatched Alloreactive Immune Response

In transplantation, direct allorecognition is a complex interplay between T-cell receptors (TCR) and HLA molecules and their bound peptides expressed on antigen-presenting cells. In analogy to HLA mismatched hematopoietic stem cell transplantation (HSCT), the TCR CDR3β repertoires of alloreactive cy...

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Detalles Bibliográficos
Autores principales: Bettens, Florence, Calderin Sollet, Zuleika, Buhler, Stéphane, Villard, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856301/
https://www.ncbi.nlm.nih.gov/pubmed/33552048
http://dx.doi.org/10.3389/fimmu.2020.588741