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Is There a Synergistic Effect of Topical Plus Intravenous Tranexamic Acid Versus Intravenous Administration Alone on Blood Loss and Transfusions in Primary Total Hip and Knee Arthroplasties?

BACKGROUND: The optimal route and dosing regimen of tranexamic acid (TXA) in primary total hip arthroplasty (THA) and total knee arthroplasty (TKA) remain unclear. As such, we sought to analyze if there was a synergistic effect of intravenous (IV) and topical TXA on blood loss and transfusions. METH...

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Detalles Bibliográficos
Autores principales: Chalmers, Brian P., Mishu, Mithun, Cushner, Fred D., Sculco, Peter K., Nguyen, Joseph, Westrich, Geoffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856320/
https://www.ncbi.nlm.nih.gov/pubmed/33553549
http://dx.doi.org/10.1016/j.artd.2020.12.024