Cargando…

Clinical experience of MRI(4D) QUASAR motion phantom for latency measurements in 0.35T MR‐LINAC

PURPOSE: In MRgRT, accuracy of treatment depends on the gating latency, when real‐time targeting and gating is enabled. Gating latency is dependent on image acquisition, processing time, accuracy, efficacy of target tracking algorithms, and radiation beam delivery latency. In this report, clinical e...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Taeho, Lewis, Benjamin, Lotey, Rajiv, Barberi, Enzo, Green, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856488/
https://www.ncbi.nlm.nih.gov/pubmed/33336884
http://dx.doi.org/10.1002/acm2.13118
_version_ 1783646261000273920
author Kim, Taeho
Lewis, Benjamin
Lotey, Rajiv
Barberi, Enzo
Green, Olga
author_facet Kim, Taeho
Lewis, Benjamin
Lotey, Rajiv
Barberi, Enzo
Green, Olga
author_sort Kim, Taeho
collection PubMed
description PURPOSE: In MRgRT, accuracy of treatment depends on the gating latency, when real‐time targeting and gating is enabled. Gating latency is dependent on image acquisition, processing time, accuracy, efficacy of target tracking algorithms, and radiation beam delivery latency. In this report, clinical experience of the MRI(4D) QUASAR motion phantom for latency measurements on a 0.35‐T magnetic resonance‐linear accelerator (MR‐LINAC) with two imaging speeds and four tracking algorithms was studied. MATERIALS/METHODS: Beam‐control latency was measured on a 0.35‐T MR‐LINAC system with four target tracking algorithms and two real‐time cine imaging sequences [four and eight frames per second (FPS)]. Using an MR‐compatible motion phantom, the delays between phantom beam triggering signal and linac radiation beam control signal were evaluated for three motion periods with a rigid target. The gating point was set to be 8 mm above the full exhalation position. The beam‐off latency was measured for a total of 24 combinations of tracking algorithm, imaging FPS, and motion periods. The corresponding gating target margins were determined using the target motion speed multiplied by the beam‐off latency. RESULTS: The largest measured beam‐off latency was 302 ± 20 ms with the Large Deforming Targets (LDT) algorithm and 4 s motion period imaged with 8‐FPS cine MRI. The corresponding gating uncertainty based on target motion speed was 3.0 mm. The range of the average beam‐off latency was 128–243 ms in 4‐FPS imaging and 47–302 ms in 8‐FPS imaging. CONCLUSIONS: The gating latency was measured using an MRI(4D) QUASAR motion phantom in a 0.35‐T MR‐LINAC. The latency measurements include time delay related to MR imaging method, target tracking algorithm and system delay. The gating uncertainty was estimated based on the beam‐off latency measurements and the target motion.
format Online
Article
Text
id pubmed-7856488
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-78564882021-02-05 Clinical experience of MRI(4D) QUASAR motion phantom for latency measurements in 0.35T MR‐LINAC Kim, Taeho Lewis, Benjamin Lotey, Rajiv Barberi, Enzo Green, Olga J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: In MRgRT, accuracy of treatment depends on the gating latency, when real‐time targeting and gating is enabled. Gating latency is dependent on image acquisition, processing time, accuracy, efficacy of target tracking algorithms, and radiation beam delivery latency. In this report, clinical experience of the MRI(4D) QUASAR motion phantom for latency measurements on a 0.35‐T magnetic resonance‐linear accelerator (MR‐LINAC) with two imaging speeds and four tracking algorithms was studied. MATERIALS/METHODS: Beam‐control latency was measured on a 0.35‐T MR‐LINAC system with four target tracking algorithms and two real‐time cine imaging sequences [four and eight frames per second (FPS)]. Using an MR‐compatible motion phantom, the delays between phantom beam triggering signal and linac radiation beam control signal were evaluated for three motion periods with a rigid target. The gating point was set to be 8 mm above the full exhalation position. The beam‐off latency was measured for a total of 24 combinations of tracking algorithm, imaging FPS, and motion periods. The corresponding gating target margins were determined using the target motion speed multiplied by the beam‐off latency. RESULTS: The largest measured beam‐off latency was 302 ± 20 ms with the Large Deforming Targets (LDT) algorithm and 4 s motion period imaged with 8‐FPS cine MRI. The corresponding gating uncertainty based on target motion speed was 3.0 mm. The range of the average beam‐off latency was 128–243 ms in 4‐FPS imaging and 47–302 ms in 8‐FPS imaging. CONCLUSIONS: The gating latency was measured using an MRI(4D) QUASAR motion phantom in a 0.35‐T MR‐LINAC. The latency measurements include time delay related to MR imaging method, target tracking algorithm and system delay. The gating uncertainty was estimated based on the beam‐off latency measurements and the target motion. John Wiley and Sons Inc. 2020-12-18 /pmc/articles/PMC7856488/ /pubmed/33336884 http://dx.doi.org/10.1002/acm2.13118 Text en © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Kim, Taeho
Lewis, Benjamin
Lotey, Rajiv
Barberi, Enzo
Green, Olga
Clinical experience of MRI(4D) QUASAR motion phantom for latency measurements in 0.35T MR‐LINAC
title Clinical experience of MRI(4D) QUASAR motion phantom for latency measurements in 0.35T MR‐LINAC
title_full Clinical experience of MRI(4D) QUASAR motion phantom for latency measurements in 0.35T MR‐LINAC
title_fullStr Clinical experience of MRI(4D) QUASAR motion phantom for latency measurements in 0.35T MR‐LINAC
title_full_unstemmed Clinical experience of MRI(4D) QUASAR motion phantom for latency measurements in 0.35T MR‐LINAC
title_short Clinical experience of MRI(4D) QUASAR motion phantom for latency measurements in 0.35T MR‐LINAC
title_sort clinical experience of mri(4d) quasar motion phantom for latency measurements in 0.35t mr‐linac
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856488/
https://www.ncbi.nlm.nih.gov/pubmed/33336884
http://dx.doi.org/10.1002/acm2.13118
work_keys_str_mv AT kimtaeho clinicalexperienceofmri4dquasarmotionphantomforlatencymeasurementsin035tmrlinac
AT lewisbenjamin clinicalexperienceofmri4dquasarmotionphantomforlatencymeasurementsin035tmrlinac
AT loteyrajiv clinicalexperienceofmri4dquasarmotionphantomforlatencymeasurementsin035tmrlinac
AT barberienzo clinicalexperienceofmri4dquasarmotionphantomforlatencymeasurementsin035tmrlinac
AT greenolga clinicalexperienceofmri4dquasarmotionphantomforlatencymeasurementsin035tmrlinac