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Portal dosimetry in radiotherapy repeatability evaluation

The accuracy of radiotherapy is the subject of continuous discussion, and dosimetry methods, particularly in dynamic techniques, are being developed. At the same time, many oncology centers develop quality procedures, including pretreatment and online dose verification and proper patient tracking me...

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Autores principales: Ślosarek, Krzysztof, Plaza, Dominika, Nas, Aleksandra, Reudelsdorf, Marta, Wendykier, Jacek, Bekman, Barbara, Grządziel, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856497/
https://www.ncbi.nlm.nih.gov/pubmed/33314643
http://dx.doi.org/10.1002/acm2.13123
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author Ślosarek, Krzysztof
Plaza, Dominika
Nas, Aleksandra
Reudelsdorf, Marta
Wendykier, Jacek
Bekman, Barbara
Grządziel, Aleksandra
author_facet Ślosarek, Krzysztof
Plaza, Dominika
Nas, Aleksandra
Reudelsdorf, Marta
Wendykier, Jacek
Bekman, Barbara
Grządziel, Aleksandra
author_sort Ślosarek, Krzysztof
collection PubMed
description The accuracy of radiotherapy is the subject of continuous discussion, and dosimetry methods, particularly in dynamic techniques, are being developed. At the same time, many oncology centers develop quality procedures, including pretreatment and online dose verification and proper patient tracking methods. This work aims to present the possibility of using portal dosimetry in the assessment of radiotherapy repeatability. The analysis was conducted on 74 cases treated with dynamic techniques. Transit dosimetry was made for each collision‐free radiation beam. It allowed the comparison of summary fluence maps, obtained for fractions with the corresponding summary maps from all other treatment fractions. For evaluation of the compatibility in the fluence map pairs (6798), the gamma coefficient was calculated. The results were considered in four groups, depending on the used radiotherapy technique: stereotactic fractionated radiotherapy, breath‐hold, free‐breathing, and conventionally fractionated other cases. The chi(2) or Fisher's exact test was made depending on the size of the analyzed set and also Mann–Whitney U‐test was used to compare treatment repeatability of different techniques. The aim was to test whether the null hypothesis of error‐free therapy was met. The patient is treated repeatedly if the P‐value in all the fluence maps sets is higher than the level of 0.01. The best compatibility between treatment fractions was obtained for the stereotactic technique. The technique with breath‐holding gave the lowest percentage of compliance of the analyzed fluence pairs. The results indicate that the repeatability of the treatment is associated with the radiotherapy technique. Treated volume location is also an essential factor found in the evaluation of treatment accuracy. The EPID device is a useful tool in assessing the repeatability of radiotherapy. The proposed method of fluence maps comparison also allows us to assess in which therapeutic session the patient was treated differently from the other fractions.
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spelling pubmed-78564972021-02-05 Portal dosimetry in radiotherapy repeatability evaluation Ślosarek, Krzysztof Plaza, Dominika Nas, Aleksandra Reudelsdorf, Marta Wendykier, Jacek Bekman, Barbara Grządziel, Aleksandra J Appl Clin Med Phys Radiation Oncology Physics The accuracy of radiotherapy is the subject of continuous discussion, and dosimetry methods, particularly in dynamic techniques, are being developed. At the same time, many oncology centers develop quality procedures, including pretreatment and online dose verification and proper patient tracking methods. This work aims to present the possibility of using portal dosimetry in the assessment of radiotherapy repeatability. The analysis was conducted on 74 cases treated with dynamic techniques. Transit dosimetry was made for each collision‐free radiation beam. It allowed the comparison of summary fluence maps, obtained for fractions with the corresponding summary maps from all other treatment fractions. For evaluation of the compatibility in the fluence map pairs (6798), the gamma coefficient was calculated. The results were considered in four groups, depending on the used radiotherapy technique: stereotactic fractionated radiotherapy, breath‐hold, free‐breathing, and conventionally fractionated other cases. The chi(2) or Fisher's exact test was made depending on the size of the analyzed set and also Mann–Whitney U‐test was used to compare treatment repeatability of different techniques. The aim was to test whether the null hypothesis of error‐free therapy was met. The patient is treated repeatedly if the P‐value in all the fluence maps sets is higher than the level of 0.01. The best compatibility between treatment fractions was obtained for the stereotactic technique. The technique with breath‐holding gave the lowest percentage of compliance of the analyzed fluence pairs. The results indicate that the repeatability of the treatment is associated with the radiotherapy technique. Treated volume location is also an essential factor found in the evaluation of treatment accuracy. The EPID device is a useful tool in assessing the repeatability of radiotherapy. The proposed method of fluence maps comparison also allows us to assess in which therapeutic session the patient was treated differently from the other fractions. John Wiley and Sons Inc. 2020-12-12 /pmc/articles/PMC7856497/ /pubmed/33314643 http://dx.doi.org/10.1002/acm2.13123 Text en © 2020 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Ślosarek, Krzysztof
Plaza, Dominika
Nas, Aleksandra
Reudelsdorf, Marta
Wendykier, Jacek
Bekman, Barbara
Grządziel, Aleksandra
Portal dosimetry in radiotherapy repeatability evaluation
title Portal dosimetry in radiotherapy repeatability evaluation
title_full Portal dosimetry in radiotherapy repeatability evaluation
title_fullStr Portal dosimetry in radiotherapy repeatability evaluation
title_full_unstemmed Portal dosimetry in radiotherapy repeatability evaluation
title_short Portal dosimetry in radiotherapy repeatability evaluation
title_sort portal dosimetry in radiotherapy repeatability evaluation
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856497/
https://www.ncbi.nlm.nih.gov/pubmed/33314643
http://dx.doi.org/10.1002/acm2.13123
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