Cargando…

A snapshot of translation in Mycobacterium tuberculosis during exponential growth and nutrient starvation revealed by ribosome profiling

Mycobacterium tuberculosis, which causes tuberculosis, can undergo prolonged periods of non-replicating persistence in the host. The mechanisms underlying this are not fully understood, but translational regulation is thought to play a role. A large proportion of mRNA transcripts expressed in M. tub...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sawyer, Elizabeth B., Phelan, Jody E., Clark, Taane G., Cortes, Teresa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2021
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856553/ https://www.ncbi.nlm.nih.gov/pubmed/33535039 http://dx.doi.org/10.1016/j.celrep.2021.108695

Ejemplares similares

Mixed infections in genotypic drug-resistant Mycobacterium tuberculosis
por: Wang, Linfeng, et al.
Publicado: (2023)

Portable sequencing of Mycobacterium tuberculosis for clinical and epidemiological applications
por: Gómez-González, Paula J, et al.
Publicado: (2022)

Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis
por: Cortes, Teresa, et al.
Publicado: (2013)

Large-scale genomic analysis of Mycobacterium tuberculosis reveals extent of target and compensatory mutations linked to multi-drug resistant tuberculosis
por: Napier, Gary, et al.
Publicado: (2023)

Understanding molecular consequences of putative drug resistant mutations in Mycobacterium tuberculosis
por: Portelli, Stephanie, et al.
Publicado: (2018)

Structure of the actively translating plant 80S ribosome at 2.2 Å resolution
por: Smirnova, Julia, et al.
Publicado: (2023)

Structural and Genomic Insights Into Pyrazinamide Resistance in Mycobacterium tuberculosis Underlie Differences Between Ancient and Modern Lineages
por: Tunstall, Tanushree, et al.
Publicado: (2021)

Translation of a Leaderless Reporter Is Robust During Exponential Growth and Well Sustained During Stress Conditions in Mycobacterium tuberculosis
por: Grabowska, Anna D., et al.
Publicado: (2021)

Emergence of multidrug-resistant Mycobacterium tuberculosis of the Beijing lineage in Portugal and Guinea-Bissau: a snapshot of moving clones by whole-genome sequencing
por: Perdigão, João, et al.
Publicado: (2020)

Robust detection of point mutations involved in multidrug-resistant Mycobacterium tuberculosis in the presence of co-occurrent resistance markers
por: Libiseller-Egger, Julian, et al.
Publicado: (2020)

Ribosome profiling enhances understanding of mycobacterial translation
por: Sawyer, Elizabeth B., et al.
Publicado: (2022)

A modified decision tree approach to improve the prediction and mutation discovery for drug resistance in Mycobacterium tuberculosis
por: Deelder, Wouter, et al.
Publicado: (2022)

Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis
por: Andreu, Nuria, et al.
Publicado: (2017)

TB-ML—a framework for comparing machine learning approaches to predict drug resistance of Mycobacterium tuberculosis
por: Libiseller-Egger, Julian, et al.
Publicado: (2023)

Feature weighted models to address lineage dependency in drug-resistance prediction from Mycobacterium tuberculosis genome sequences
por: Billows, Nina, et al.
Publicado: (2023)

Robust barcoding and identification of Mycobacterium tuberculosis lineages for epidemiological and clinical studies
por: Napier, Gary, et al.
Publicado: (2020)

Whole genome sequencing reveals large deletions and other loss of function mutations in Mycobacterium tuberculosis drug resistance genes
por: Gomes, Laura C., et al.
Publicado: (2021)

Proteomic Profiling of Mycobacterium tuberculosis Identifies Nutrient-starvation-responsive Toxin–antitoxin Systems
por: Albrethsen, Jakob, et al.
Publicado: (2013)

Loss of the starvation-induced gene Rack1 leads to glycogen deficiency and impaired autophagic responses in Drosophila
por: Érdi, Balázs, et al.
Publicado: (2012)

Machine Learning Predicts Accurately Mycobacterium tuberculosis Drug Resistance From Whole Genome Sequencing Data
por: Deelder, Wouter, et al.
Publicado: (2019)

Comparison of in silico predicted Mycobacterium tuberculosis spoligotypes and lineages from whole genome sequencing data
por: Napier, Gary, et al.
Publicado: (2023)

Assessing the translational landscape of myogenic differentiation by ribosome profiling
por: de Klerk, Eleonora, et al.
Publicado: (2015)

Genome-wide analysis of Mycobacterium tuberculosis polymorphisms reveals lineage-specific associations with drug resistance
por: Oppong, Yaa E. A., et al.
Publicado: (2019)

Emergence of the primordial pre-60S from the 90S pre-ribosome
por: Ismail, Sherif, et al.
Publicado: (2022)

Death of Mycobacterium tuberculosis by l-arginine starvation
por: Mizrahi, Valerie, et al.
Publicado: (2018)

The COMBAT-TB Workbench: Making Powerful Mycobacterium tuberculosis Bioinformatics Accessible
por: van Heusden, Peter, et al.
Publicado: (2022)

Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach
por: Meyer, Pablo, et al.
Publicado: (2013)

Exploring bacterial diversity via a curated and searchable snapshot of archived DNA sequences
por: Blackwell, Grace A., et al.
Publicado: (2021)

Human pluripotent stem cell-derived macrophages host Mycobacterium abscessus infection
por: Sun, Shicheng, et al.
Publicado: (2022)

Decreased synthesis of ribosomal proteins in tauopathy revealed by non‐canonical amino acid labelling
por: Evans, Harrison Tudor, et al.
Publicado: (2019)

Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue
por: Parasa, Venkata Ramanarao, et al.
Publicado: (2014)

Functional genetic variation in pe/ppe genes contributes to diversity in Mycobacterium tuberculosis lineages and potential interactions with the human host
por: Gómez-González, Paula Josefina, et al.
Publicado: (2023)

Characterization of rifampicin-resistant Mycobacterium tuberculosis in Khyber Pakhtunkhwa, Pakistan
por: Khan, Anwar Sheed, et al.
Publicado: (2021)

Microfluidic Capture of Mycobacterium tuberculosis from Clinical Samples for Culture-Free Whole-Genome Sequencing
por: Ismail, Nabila, et al.
Publicado: (2023)

Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates
por: Gladstone, Rebecca A., et al.
Publicado: (2020)

Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid
por: Gómez-González, Paula J., et al.
Publicado: (2021)

Translation and Replication Dynamics of Single RNA Viruses
por: Boersma, Sanne, et al.
Publicado: (2020)

Characterisation of drug-resistant Mycobacterium tuberculosis mutations and transmission in Pakistan
por: Napier, Gary, et al.
Publicado: (2022)

Correlative light electron ion microscopy reveals in vivo localisation of bedaquiline in Mycobacterium tuberculosis–infected lungs
por: Fearns, Antony, et al.
Publicado: (2020)

Dynamics of Translation of Single mRNA Molecules In Vivo
por: Yan, Xiaowei, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_na3cg4v91cn1a5dijjjb5phh0o