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Determining sample size for progression criteria for pragmatic pilot RCTs: the hypothesis test strikes back!
BACKGROUND: The current CONSORT guidelines for reporting pilot trials do not recommend hypothesis testing of clinical outcomes on the basis that a pilot trial is under-powered to detect such differences and this is the aim of the main trial. It states that primary evaluation should focus on descript...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856754/ https://www.ncbi.nlm.nih.gov/pubmed/33536076 http://dx.doi.org/10.1186/s40814-021-00770-x |