Cargando…

Cholesterol in the Viral Membrane is a Molecular Switch Governing HIV‐1 Env Clustering

HIV‐1 entry requires the redistribution of envelope glycoproteins (Env) into a cluster and the presence of cholesterol (chol) in the viral membrane. However, the molecular mechanisms underlying the specific role of chol in infectivity and the driving force behind Env clustering remain unknown. Here,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nieto‐Garai, Jon Ander, Arboleya, Aroa, Otaegi, Sara, Chojnacki, Jakub, Casas, Josefina, Fabriàs, Gemma, Contreras, F‐Xabier, Kräusslich, Hans‐Georg, Lorizate, Maier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7856888/ https://www.ncbi.nlm.nih.gov/pubmed/33552873 http://dx.doi.org/10.1002/advs.202003468

Ejemplares similares

Identification of a New Cholesterol‐Binding Site within the IFN‐γ Receptor that is Required for Signal Transduction
por: Morana, Ornella, et al.
Publicado: (2022)

Sialyllactose in Viral Membrane Gangliosides Is a Novel Molecular Recognition Pattern for Mature Dendritic Cell Capture of HIV-1
por: Izquierdo-Useros, Nuria, et al.
Publicado: (2012)

Raman Spectroscopy as a Tool to Study the Pathophysiology of Brain Diseases
por: Terrones, Oihana, et al.
Publicado: (2023)

Super-Resolution Microscopy to Study Interorganelle Contact Sites
por: Nieto-Garai, Jon Ander, et al.
Publicado: (2022)

Lipidomimetic Compounds Act as HIV-1 Entry Inhibitors by Altering Viral Membrane Structure
por: Nieto-Garai, Jon Ander, et al.
Publicado: (2018)

Functional organization of the HIV lipid envelope
por: Huarte, Nerea, et al.
Publicado: (2016)

Coordinated changes of HIV-1 Gag and Env during assembly and maturation
por: Kräusslich, Hans-Georg
Publicado: (2013)

Diets with Higher ω-6/ω-3 Ratios Show Differences in Ceramides and Fatty Acid Levels Accompanied by Increased Amyloid-Beta in the Brains of Male APP/PS1 Transgenic Mice
por: Ordóñez-Gutiérrez, Lara, et al.
Publicado: (2021)

Super-Resolution STED Microscopy-Based Mobility Studies of the Viral Env Protein at HIV-1 Assembly Sites of Fully Infected T-Cells
por: Chojnacki, Jakub, et al.
Publicado: (2021)

High-throughput discovery of novel small-molecule inhibitors of acid Ceramidase
por: Aseeri, Mazen, et al.
Publicado: (2022)

Actin-regulated Siglec-1 nanoclustering influences HIV-1 capture and virus-containing compartment formation in dendritic cells
por: Gutiérrez-Martínez, Enric, et al.
Publicado: (2023)

Envés
por: Amara, Luigi, 1971-
Publicado: (2003)

HIV-1 Capture and Transmission by Dendritic Cells: The Role of Viral Glycolipids and the Cellular Receptor Siglec-1
por: Izquierdo-Useros, Nuria, et al.
Publicado: (2014)

Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation
por: Torres, Sandra, et al.
Publicado: (2021)

Methuosis Contributes to Jaspine-B-Induced Cell Death
por: Bielsa, Núria, et al.
Publicado: (2022)

Plasmalogen enrichment in exosomes secreted by a nematode parasite versus those derived from its mouse host: implications for exosome stability and biology
por: Simbari, Fabio, et al.
Publicado: (2016)

Impact of Cancer Stem Cells on Therapy Resistance in Gastric Cancer
por: Otaegi-Ugartemendia, Maddalen, et al.
Publicado: (2022)

A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors
por: Mira, Emilia, et al.
Publicado: (2013)

Intermediary organisations in collaborative environmental governance: evidence of the EU-funded LIFE sub-programme for the environment (LIFE-ENV)
por: Pisani, Elena, et al.
Publicado: (2020)

Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif
por: Molinos-Albert, Luis M., et al.
Publicado: (2017)

Click and count: specific detection of acid ceramidase activity in live cells
por: Casasampere, Mireia, et al.
Publicado: (2020)

The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions
por: Herschhorn, Alon, et al.
Publicado: (2017)

Obesogens beyond Vertebrates: Lipid Perturbation by Tributyltin in the Crustacean Daphnia magna
por: Jordão, Rita, et al.
Publicado: (2015)

Maternal intranasal immunization with HTLV-1 Env induces Env specific antibody responses in breast milk
por: Suzuki, Tadaki
Publicado: (2015)

Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis
por: Martínez, Laura, et al.
Publicado: (2015)

Vista envés de un cuerpo /
por: Homero, José, 1965-
Publicado: (2000)

Vista envés de un cuerpo
por: Homero, José
Publicado: (2019)

EnvIRONmental Aspects in Myelodysplastic Syndrome
por: Petzer, Verena, et al.
Publicado: (2021)

CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo
por: Tsao, Li-Chung, et al.
Publicado: (2016)

Publisher Correction: The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions
por: Herschhorn, Alon, et al.
Publicado: (2018)

On-Tissue Localization of Ceramides and Other Sphingolipids by MALDI Mass Spectrometry Imaging
por: Jones, E. Ellen, et al.
Publicado: (2014)

Viral vector delivery of Env trimer immunogens
por: Parks, CL, et al.
Publicado: (2012)

geoENV VII – Geostatistics for Environmental Applications
por: Atkinson, P, et al.
Publicado: (2010)

EnvStats: an R package for environmental statistics
por: Millard, Steven P
Publicado: (2013)

Retroviral Env Glycoprotein Trafficking and Incorporation into Virions
por: Murakami, Tsutomu
Publicado: (2012)

Sequencing the Biology of Entry: The Retroviral env Gene
por: Swanstrom, Ronald, et al.
Publicado: (2017)

Analysis of transcribed human endogenous retrovirus W env loci clarifies the origin of multiple sclerosis-associated retrovirus env sequences
por: Laufer, Georg, et al.
Publicado: (2009)

Structural characterization of HIV-1 Env heterotrimers bound to one or two CD4 receptors reveals intermediate Env conformations
por: Dam, Kim-Marie A., et al.
Publicado: (2023)

Isolation and purification of HIV-1 LTR circles from PBMCs for the analysis of episomal env sequences
por: González, Sandra, et al.
Publicado: (2006)

Interfacial pre-transmembrane domains in viral proteins promoting membrane fusion and fission
por: Lorizate, Maier, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_b0b893ckehrl7crht5jn36j36i