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Phosphoinositide 3-Kinase Signaling in the Tumor Microenvironment: What Do We Need to Consider When Treating Chronic Lymphocytic Leukemia With PI3K Inhibitors?

Phosphoinositide 3-kinases (PI3Ks) and their downstream proteins constitute a signaling pathway that is involved in both normal cell growth and malignant transformation of cells. Under physiological conditions, PI3K signaling regulates various cellular functions such as apoptosis, survival, prolifer...

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Detalles Bibliográficos
Autores principales:	Aydin, Ebru, Faehling, Sebastian, Saleh, Mariam, Llaó Cid, Laura, Seiffert, Martina, Roessner, Philipp M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857022/ https://www.ncbi.nlm.nih.gov/pubmed/33552053 http://dx.doi.org/10.3389/fimmu.2020.595818

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