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SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO

Coronavirus disease 2019 (COVID-19) is a current global health threat caused by the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Emerging evidence indicates that SARS-CoV-2 elicits a dysregulated immune response and a delayed interferon (IFN) expression in patients...

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Detalles Bibliográficos
Autores principales:	Wu, Jing, Shi, Yuheng, Pan, Xiaoyan, Wu, Shuang, Hou, Ruixia, Zhang, Yong, Zhong, Tiansheng, Tang, Hao, Du, Wei, Wang, Luying, Wo, Jing, Mu, Jingfang, Qiu, Yang, Yang, Ke, Zhang, Lei-Ke, Ye, Bang-Ce, Qi, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Author(s). 2021
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857071/ https://www.ncbi.nlm.nih.gov/pubmed/33567255 http://dx.doi.org/10.1016/j.celrep.2021.108761

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