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Age-dependent effects of the recombinant spike protein/SARS-CoV-2 on the M–CSF– and IL-34-differentiated macrophages in vitro

The SARS-CoV-2 virus causes elevated production of senescence-associated secretory phenotype (SASP) markers by macrophages. SARS-CoV-2 enters macrophages through its Spike-protein aided by cathepsin (Cat) B and L, which also mediate SASP production. Since M-CSF and IL-34 control macrophage different...

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Detalles Bibliográficos
Autores principales:	Duarte, Carolina, Akkaoui, Juliet, Ho, Anny, Garcia, Christopher, Yamada, Chiaki, Movila, Alexandru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857081/ https://www.ncbi.nlm.nih.gov/pubmed/33578295 http://dx.doi.org/10.1016/j.bbrc.2021.01.104

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