A Highly Reproducible Micro U‐Well Array Plate Facilitating High‐Throughput Tumor Spheroid Culture and Drug Assessment (Global Challenges 2/2021)

In article number 2000056 Ting‐Yuan Tu and co‐workers demonstrate a facile and highly reproducible laser‐ablated micro U‐well with optimal array arrangement. Cell‐loss free formation of multicellular tumor spheroids is performed in 96‐well plates for high‐throughput drug screening of cisplatin. Dose...

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Autores principales: Wu, Kuang‐Wei, Kuo, Ching‐Te, Tu, Ting‐Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Cover Picture
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857124/
http://dx.doi.org/10.1002/gch2.202170021
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author Wu, Kuang‐Wei
Kuo, Ching‐Te
Tu, Ting‐Yuan
author_facet Wu, Kuang‐Wei
Kuo, Ching‐Te
Tu, Ting‐Yuan
author_sort Wu, Kuang‐Wei
collection PubMed
description In article number 2000056 Ting‐Yuan Tu and co‐workers demonstrate a facile and highly reproducible laser‐ablated micro U‐well with optimal array arrangement. Cell‐loss free formation of multicellular tumor spheroids is performed in 96‐well plates for high‐throughput drug screening of cisplatin. Dose‐response assays are investigated on T24, A549, and Huh‐7 in both 2D and multicellular tumor spheroid (MCTS) conditions. The permeability dynamics of each type of MCTS are examined. [Image: see text]
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spelling pubmed-78571242021-02-05 A Highly Reproducible Micro U‐Well Array Plate Facilitating High‐Throughput Tumor Spheroid Culture and Drug Assessment (Global Challenges 2/2021) Wu, Kuang‐Wei Kuo, Ching‐Te Tu, Ting‐Yuan Glob Chall Cover Picture In article number 2000056 Ting‐Yuan Tu and co‐workers demonstrate a facile and highly reproducible laser‐ablated micro U‐well with optimal array arrangement. Cell‐loss free formation of multicellular tumor spheroids is performed in 96‐well plates for high‐throughput drug screening of cisplatin. Dose‐response assays are investigated on T24, A549, and Huh‐7 in both 2D and multicellular tumor spheroid (MCTS) conditions. The permeability dynamics of each type of MCTS are examined. [Image: see text] John Wiley and Sons Inc. 2021-02-03 /pmc/articles/PMC7857124/ http://dx.doi.org/10.1002/gch2.202170021 Text en © 2021 Wiley‐VCH GmbH This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Cover Picture
Wu, Kuang‐Wei
Kuo, Ching‐Te
Tu, Ting‐Yuan
A Highly Reproducible Micro U‐Well Array Plate Facilitating High‐Throughput Tumor Spheroid Culture and Drug Assessment (Global Challenges 2/2021)
title A Highly Reproducible Micro U‐Well Array Plate Facilitating High‐Throughput Tumor Spheroid Culture and Drug Assessment (Global Challenges 2/2021)
title_full A Highly Reproducible Micro U‐Well Array Plate Facilitating High‐Throughput Tumor Spheroid Culture and Drug Assessment (Global Challenges 2/2021)
title_fullStr A Highly Reproducible Micro U‐Well Array Plate Facilitating High‐Throughput Tumor Spheroid Culture and Drug Assessment (Global Challenges 2/2021)
title_full_unstemmed A Highly Reproducible Micro U‐Well Array Plate Facilitating High‐Throughput Tumor Spheroid Culture and Drug Assessment (Global Challenges 2/2021)
title_short A Highly Reproducible Micro U‐Well Array Plate Facilitating High‐Throughput Tumor Spheroid Culture and Drug Assessment (Global Challenges 2/2021)
title_sort highly reproducible micro u‐well array plate facilitating high‐throughput tumor spheroid culture and drug assessment (global challenges 2/2021)
topic Cover Picture
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857124/
http://dx.doi.org/10.1002/gch2.202170021
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