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Respiratory infections: Role of Vitamin D and surfactant proteins A and D
Respiratory tract infection is the common viral infection and the principal cause of death among children under 5 years of age. It damages lung epithelium and increases mucus production and inflammation, leading to dyspnea. The sunshine vitamin (Vitamin D) and surfactant protein (SP) A and D along w...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857376/ https://www.ncbi.nlm.nih.gov/pubmed/32883903 http://dx.doi.org/10.4103/lungindia.lungindia_369_18 |
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author | Poorna, Rachel Biswal, Niranjan |
author_facet | Poorna, Rachel Biswal, Niranjan |
author_sort | Poorna, Rachel |
collection | PubMed |
description | Respiratory tract infection is the common viral infection and the principal cause of death among children under 5 years of age. It damages lung epithelium and increases mucus production and inflammation, leading to dyspnea. The sunshine vitamin (Vitamin D) and surfactant protein (SP) A and D along with their usual function play an important role in host defense. This article reviews with immune role of Vitamin D and SP A and D which aids excessive cytokines production, boosts phagocytosis, hinders inflammatory activity, and thus acts as a first-line defense against lung pathogens. |
format | Online Article Text |
id | pubmed-7857376 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-78573762021-02-05 Respiratory infections: Role of Vitamin D and surfactant proteins A and D Poorna, Rachel Biswal, Niranjan Lung India Review Article Respiratory tract infection is the common viral infection and the principal cause of death among children under 5 years of age. It damages lung epithelium and increases mucus production and inflammation, leading to dyspnea. The sunshine vitamin (Vitamin D) and surfactant protein (SP) A and D along with their usual function play an important role in host defense. This article reviews with immune role of Vitamin D and SP A and D which aids excessive cytokines production, boosts phagocytosis, hinders inflammatory activity, and thus acts as a first-line defense against lung pathogens. Wolters Kluwer - Medknow 2020 2020-08-31 /pmc/articles/PMC7857376/ /pubmed/32883903 http://dx.doi.org/10.4103/lungindia.lungindia_369_18 Text en Copyright: © 2020 Indian Chest Society http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Review Article Poorna, Rachel Biswal, Niranjan Respiratory infections: Role of Vitamin D and surfactant proteins A and D |
title | Respiratory infections: Role of Vitamin D and surfactant proteins A and D |
title_full | Respiratory infections: Role of Vitamin D and surfactant proteins A and D |
title_fullStr | Respiratory infections: Role of Vitamin D and surfactant proteins A and D |
title_full_unstemmed | Respiratory infections: Role of Vitamin D and surfactant proteins A and D |
title_short | Respiratory infections: Role of Vitamin D and surfactant proteins A and D |
title_sort | respiratory infections: role of vitamin d and surfactant proteins a and d |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857376/ https://www.ncbi.nlm.nih.gov/pubmed/32883903 http://dx.doi.org/10.4103/lungindia.lungindia_369_18 |
work_keys_str_mv | AT poornarachel respiratoryinfectionsroleofvitamindandsurfactantproteinsaandd AT biswalniranjan respiratoryinfectionsroleofvitamindandsurfactantproteinsaandd |