Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

Efficient therapeutic options are needed to control the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has caused more than 922,000 fatalities as of 13 September 2020. We report the isolation and characterization of two ultrapotent SARS-CoV-2 human neutralizing antibodie...

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Autores principales: Tortorici, M. Alejandra, Beltramello, Martina, Lempp, Florian A., Pinto, Dora, Dang, Ha V., Rosen, Laura E., McCallum, Matthew, Bowen, John, Minola, Andrea, Jaconi, Stefano, Zatta, Fabrizia, De Marco, Anna, Guarino, Barbara, Bianchi, Siro, Lauron, Elvin J., Tucker, Heather, Zhou, Jiayi, Peter, Alessia, Havenar-Daughton, Colin, Wojcechowskyj, Jason A., Case, James Brett, Chen, Rita E., Kaiser, Hannah, Montiel-Ruiz, Martin, Meury, Marcel, Czudnochowski, Nadine, Spreafico, Roberto, Dillen, Josh, Ng, Cindy, Sprugasci, Nicole, Culap, Katja, Benigni, Fabio, Abdelnabi, Rana, Foo, Shi-Yan Caroline, Schmid, Michael A., Cameroni, Elisabetta, Riva, Agostino, Gabrieli, Arianna, Galli, Massimo, Pizzuto, Matteo S., Neyts, Johan, Diamond, Michael S., Virgin, Herbert W., Snell, Gyorgy, Corti, Davide, Fink, Katja, Veesler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857395/
https://www.ncbi.nlm.nih.gov/pubmed/32972994
http://dx.doi.org/10.1126/science.abe3354

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