Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

Zoonotic introduction of novel coronaviruses may encounter preexisting immunity in humans. Using diverse assays for antibodies recognizing SARS-CoV-2 proteins, we detected preexisting humoral immunity. SARS-CoV-2 spike glycoprotein (S)–reactive antibodies were detectable using a flow cytometry–based...

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Detalles Bibliográficos
Autores principales: Ng, Kevin W., Faulkner, Nikhil, Cornish, Georgina H., Rosa, Annachiara, Harvey, Ruth, Hussain, Saira, Ulferts, Rachel, Earl, Christopher, Wrobel, Antoni G., Benton, Donald J., Roustan, Chloe, Bolland, William, Thompson, Rachael, Agua-Doce, Ana, Hobson, Philip, Heaney, Judith, Rickman, Hannah, Paraskevopoulou, Stavroula, Houlihan, Catherine F., Thomson, Kirsty, Sanchez, Emilie, Shin, Gee Yen, Spyer, Moira J., Joshi, Dhira, O’Reilly, Nicola, Walker, Philip A., Kjaer, Svend, Riddell, Andrew, Moore, Catherine, Jebson, Bethany R., Wilkinson, Meredyth, Marshall, Lucy R., Rosser, Elizabeth C., Radziszewska, Anna, Peckham, Hannah, Ciurtin, Coziana, Wedderburn, Lucy R., Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Stockinger, Brigitta, McCauley, John, Gamblin, Steve J., McCoy, Laura E., Cherepanov, Peter, Nastouli, Eleni, Kassiotis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857411/
https://www.ncbi.nlm.nih.gov/pubmed/33159009
http://dx.doi.org/10.1126/science.abe1107

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