Protection of dopamine neurons by CDNF and neurturin variant N4 against MPP(+) in dissociated cultures from rat mesencephalon

Parkinson’s disease is associated with the loss of dopamine (DA) neurons in ventral mesencephalon. We have previously reported that no single neurotrophic factor we tested protected DA neurons from the dopaminergic toxin 1-methyl-4-phenylpyridinium (MPP(+)) in dissociated cultures isolated from the...

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Detalles Bibliográficos
Autores principales: Jaumotte, Juliann D., Saarma, Mart, Zigmond, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857574/
https://www.ncbi.nlm.nih.gov/pubmed/33534843
http://dx.doi.org/10.1371/journal.pone.0245663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857574/
https://www.ncbi.nlm.nih.gov/pubmed/33534843
http://dx.doi.org/10.1371/journal.pone.0245663

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