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The BMP signaling gradient is interpreted through concentration thresholds in dorsal–ventral axial patterning

Bone Morphogenetic Protein (BMP) patterns the dorsal–ventral (DV) embryonic axis in all vertebrates, but it is unknown how cells along the DV axis interpret and translate the gradient of BMP signaling into differential gene activation that will give rise to distinct cell fates. To determine the mech...

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Detalles Bibliográficos
Autores principales: Greenfeld, Hannah, Lin, Jerome, Mullins, Mary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857602/
https://www.ncbi.nlm.nih.gov/pubmed/33481775
http://dx.doi.org/10.1371/journal.pbio.3001059