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Pten regulates collagen fibrillogenesis by fibroblasts through SPARC

Collagen deposition contributes to both high mammographic density and breast cancer progression. Low stromal PTEN expression has been observed in as many as half of breast tumors and is associated with increases in collagen deposition, however the mechanism connecting PTEN loss to increased collagen...

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Detalles Bibliográficos
Autores principales: Jones, Caitlin E., Sharick, Joe T., Colbert, Sheila E., Shukla, Vasudha C., Zent, Joshua M., Ostrowski, Michael C., Ghadiali, Samir N., Sizemore, Steven T., Leight, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857610/
https://www.ncbi.nlm.nih.gov/pubmed/33534863
http://dx.doi.org/10.1371/journal.pone.0245653