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Pten regulates collagen fibrillogenesis by fibroblasts through SPARC
Collagen deposition contributes to both high mammographic density and breast cancer progression. Low stromal PTEN expression has been observed in as many as half of breast tumors and is associated with increases in collagen deposition, however the mechanism connecting PTEN loss to increased collagen...
Autores principales: | Jones, Caitlin E., Sharick, Joe T., Colbert, Sheila E., Shukla, Vasudha C., Zent, Joshua M., Ostrowski, Michael C., Ghadiali, Samir N., Sizemore, Steven T., Leight, Jennifer L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857610/ https://www.ncbi.nlm.nih.gov/pubmed/33534863 http://dx.doi.org/10.1371/journal.pone.0245653 |
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