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Analysis of COVID-19 epidemic and clinical risk factors of patients under epidemiological Markov model

OBJECTIVE: It aimed to analyze the epidemic situation of new coronary pneumonia (COVID-19) based on the epidemiological Markov model, and to study the clinical risk factors of the patients based on the patient’s cardinal data and clinical symptoms. METHODS: A total of 500 patients with COVID-19 diag...

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Autores principales: Zhang, Wei, Zhang, Caiping, Bi, Yifang, Yuan, Lirong, Jiang, Yi, Hasi, Chaolu, Zhang, Xinri, Kong, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857990/
https://www.ncbi.nlm.nih.gov/pubmed/33558843
http://dx.doi.org/10.1016/j.rinp.2021.103881
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author Zhang, Wei
Zhang, Caiping
Bi, Yifang
Yuan, Lirong
Jiang, Yi
Hasi, Chaolu
Zhang, Xinri
Kong, Xiaomei
author_facet Zhang, Wei
Zhang, Caiping
Bi, Yifang
Yuan, Lirong
Jiang, Yi
Hasi, Chaolu
Zhang, Xinri
Kong, Xiaomei
author_sort Zhang, Wei
collection PubMed
description OBJECTIVE: It aimed to analyze the epidemic situation of new coronary pneumonia (COVID-19) based on the epidemiological Markov model, and to study the clinical risk factors of the patients based on the patient’s cardinal data and clinical symptoms. METHODS: A total of 500 patients with COVID-19 diagnosed by nucleic acid testing in the X hospital from January 2020 to May 2020 were collected. According to the severity of the disease, they were classified into general group (200 cases) and acute critical group (300 cases). Markov model to predict the number of COVID-19 infections was constructed. Patient’s general information, clinical characteristics, and prevention methods were analyzed. RESULTS: According to Markov model statistics, the developmental expected stay time of patients infected with COVID-19 was 14 days. 2. The two groups of patients had statistically considerable differences in complications such as gender, age, hypertension, coronary heart disease, shortness of breath, myocardial damage, and thrombocytopenia (P < 0.05). 3. Logistic multivariate regression analysis showed that the clinical risk factors for patients with COVID-19 mainly included the patient’s gender, age, whether they were associated with hypertension, coronary heart disease, shortness of breath, myocardial damage, and thrombocytopenia. CONCLUSION: Markov model can be utilized to judge the time course of the COVID-19 in various development states. In addition, the COVID-19 spread rapidly and is extremely harmful. Clinically, through active prevention, the treatment effect can be improved, the patient’s respiratory function, and the quality of life can also be improved.
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spelling pubmed-78579902021-02-04 Analysis of COVID-19 epidemic and clinical risk factors of patients under epidemiological Markov model Zhang, Wei Zhang, Caiping Bi, Yifang Yuan, Lirong Jiang, Yi Hasi, Chaolu Zhang, Xinri Kong, Xiaomei Results Phys Article OBJECTIVE: It aimed to analyze the epidemic situation of new coronary pneumonia (COVID-19) based on the epidemiological Markov model, and to study the clinical risk factors of the patients based on the patient’s cardinal data and clinical symptoms. METHODS: A total of 500 patients with COVID-19 diagnosed by nucleic acid testing in the X hospital from January 2020 to May 2020 were collected. According to the severity of the disease, they were classified into general group (200 cases) and acute critical group (300 cases). Markov model to predict the number of COVID-19 infections was constructed. Patient’s general information, clinical characteristics, and prevention methods were analyzed. RESULTS: According to Markov model statistics, the developmental expected stay time of patients infected with COVID-19 was 14 days. 2. The two groups of patients had statistically considerable differences in complications such as gender, age, hypertension, coronary heart disease, shortness of breath, myocardial damage, and thrombocytopenia (P < 0.05). 3. Logistic multivariate regression analysis showed that the clinical risk factors for patients with COVID-19 mainly included the patient’s gender, age, whether they were associated with hypertension, coronary heart disease, shortness of breath, myocardial damage, and thrombocytopenia. CONCLUSION: Markov model can be utilized to judge the time course of the COVID-19 in various development states. In addition, the COVID-19 spread rapidly and is extremely harmful. Clinically, through active prevention, the treatment effect can be improved, the patient’s respiratory function, and the quality of life can also be improved. The Author(s). Published by Elsevier B.V. 2021-03 2021-02-04 /pmc/articles/PMC7857990/ /pubmed/33558843 http://dx.doi.org/10.1016/j.rinp.2021.103881 Text en © 2021 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Zhang, Wei
Zhang, Caiping
Bi, Yifang
Yuan, Lirong
Jiang, Yi
Hasi, Chaolu
Zhang, Xinri
Kong, Xiaomei
Analysis of COVID-19 epidemic and clinical risk factors of patients under epidemiological Markov model
title Analysis of COVID-19 epidemic and clinical risk factors of patients under epidemiological Markov model
title_full Analysis of COVID-19 epidemic and clinical risk factors of patients under epidemiological Markov model
title_fullStr Analysis of COVID-19 epidemic and clinical risk factors of patients under epidemiological Markov model
title_full_unstemmed Analysis of COVID-19 epidemic and clinical risk factors of patients under epidemiological Markov model
title_short Analysis of COVID-19 epidemic and clinical risk factors of patients under epidemiological Markov model
title_sort analysis of covid-19 epidemic and clinical risk factors of patients under epidemiological markov model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857990/
https://www.ncbi.nlm.nih.gov/pubmed/33558843
http://dx.doi.org/10.1016/j.rinp.2021.103881
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