Cargando…

TGFβ promotes YAP‐dependent AXL induction in mesenchymal‐type lung cancer cells

The acquisition of chemoresistance remains a major cause of cancer mortality due to the limited accessibility of targeted or immune therapies. However, given that severe alterations of molecular features during epithelial‐to‐mesenchymal transition (EMT) lead to acquired chemoresistance, emerging stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choi, Jeong‐Yun, Lee, Haeseung, Kwon, Eun‐Ji, Kong, Hyeon‐Joon, Kwon, Ok‐Seon, Cha, Hyuk‐Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858114/ https://www.ncbi.nlm.nih.gov/pubmed/33207077 http://dx.doi.org/10.1002/1878-0261.12857

Ejemplares similares

Systematic identification of a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis
por: Kwon, Ok-Seon, et al.
Publicado: (2020)

Large-scale pharmacogenomics based drug discovery for ITGB3 dependent chemoresistance in mesenchymal lung cancer
por: Hong, Soon-Ki, et al.
Publicado: (2018)

TPX2 prompts mitotic survival via the induction of BCL2L1 through YAP1 protein stabilization in human embryonic stem cells
por: Kim, Yun-Jeong, et al.
Publicado: (2023)

YAP-Dependent AXL Overexpression Mediates Resistance to EGFR Inhibitors in NSCLC
por: Ghiso, Elena, et al.
Publicado: (2017)

ERK Dephosphorylation through MKP1 Deacetylation by SIRT1 Attenuates RAS-Driven Tumorigenesis
por: Kwon, Ok-Seon, et al.
Publicado: (2020)

Dual inhibition of TGFβ and AXL as a novel therapy for human colorectal adenocarcinoma with mesenchymal phenotype
por: Ciardiello, Davide, et al.
Publicado: (2021)

Chronic TGFβ stimulation promotes the metastatic potential of lung cancer cells by Snail protein stabilization through integrin β3-Akt-GSK3β signaling
por: Bae, Gab-Yong, et al.
Publicado: (2016)

A dual role of YAP in driving TGFβ-mediated endothelial-to-mesenchymal transition
por: Savorani, Cecilia, et al.
Publicado: (2021)

Synergistic Induction of Apoptosis by the Combination of an Axl Inhibitor and Auranofin in Human Breast Cancer Cells
por: Ryu, Yeon-Sang, et al.
Publicado: (2020)

Suppression of SIRT2 and altered acetylation status of human pluripotent stem cells: possible link to metabolic switch during reprogramming
por: Kwon, Ok-Seon, et al.
Publicado: (2017)

Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1
por: Cha, Byong-Ki, et al.
Publicado: (2016)

Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge
por: Piersma, Bram, et al.
Publicado: (2015)

Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow
por: Yumoto, Kenji, et al.
Publicado: (2016)

The TGF(β)→TAK1→LATS→YAP1 Pathway Regulates the Spatiotemporal Dynamics of YAP1
por: Kim, Min-Kyu, et al.
Publicado: (2023)

The Tumor Suppressor CYLD Inhibits Mammary Epithelial to Mesenchymal Transition by the Coordinated Inhibition of YAP/TAZ and TGFβ Signaling
por: Pseftogas, Athanasios, et al.
Publicado: (2020)

Transcriptional activators YAP/TAZ and AXL orchestrate dedifferentiation, cell fate, and metastasis in human osteosarcoma
por: Lamhamedi-Cherradi, Salah-Eddine, et al.
Publicado: (2021)

Formin-dependent TGF-β signaling for epithelial to mesenchymal transition
por: Rana, Manish K., et al.
Publicado: (2018)

Integrin β3 Promotes Resistance to EGFR-TKI in Non-Small-Cell Lung Cancer by Upregulating AXL through the YAP Pathway
por: Sun, Qi, et al.
Publicado: (2022)

Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis
por: Bauer, Thomas, et al.
Publicado: (2012)

Porphyromonas gingivalis promotes progression of esophageal squamous cell cancer via TGFβ-dependent Smad/YAP/TAZ signaling
por: Qi, Yi-Jun, et al.
Publicado: (2020)

Structure-Activity Relationship Analysis of YM155 for Inducing Selective Cell Death of Human Pluripotent Stem Cells
por: Go, Young-Hyun, et al.
Publicado: (2019)

YAP is essential for TGF‐β‐induced retinal fibrosis in diabetic rats via promoting the fibrogenic activity of Müller cells
por: Zhang, Wei, et al.
Publicado: (2020)

Stochastic and Heterogeneous Cancer Cell Migration: Experiment and Theory
por: Kwon, Taejin, et al.
Publicado: (2019)

YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts
por: Qin, Zhaoping, et al.
Publicado: (2018)

Screening of cytotoxic or cytostatic flavonoids with quantitative Fluorescent Ubiquitination-based Cell Cycle Indicator-based cell cycle assay
por: Go, Young-Hyun, et al.
Publicado: (2018)

Akt signaling is activated by TGFβ2 and impacts tenogenic induction of mesenchymal stem cells
por: Theodossiou, Sophia K., et al.
Publicado: (2021)

GPCR-induced YAP activation sensitizes fibroblasts to profibrotic activity of TGFβ1
por: Zmajkovicova, Katarina, et al.
Publicado: (2020)

Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis
por: Morice, Sarah, et al.
Publicado: (2021)

YAP/TAZ Mediate TGFβ2-Induced Schlemm's Canal Cell Dysfunction
por: Li, Haiyan, et al.
Publicado: (2022)

Hippo-YAP/TAZ signaling in angiogenesis
por: Park, Jeong Ae, et al.
Publicado: (2018)

Geranylgeraniol prevents zoledronic acid-mediated reduction of viable mesenchymal stem cells via induction of Rho-dependent YAP activation
por: Singhatanadgit, Weerachai, et al.
Publicado: (2021)

Regulation of Complement Dependent Cytotoxicity by TGF-β-induced Epithelial-Mesenchymal Transition
por: Goswami, Moloy T., et al.
Publicado: (2015)

β-catenin activates TGF-β-induced epithelial–mesenchymal transition in adenomyosis
por: Yoo, Jung-Yoon, et al.
Publicado: (2020)

β-Arrestin 2 suppresses the activation of YAP by promoting LATS kinase activity
por: Kim, Minsuh, et al.
Publicado: (2022)

Regulatory T Cells Induce Metastasis by Activating Tgf-Β and Enhancing the Epithelial–Mesenchymal Transition
por: Oh, Eonju, et al.
Publicado: (2019)

Hierarchy of TGFβ/SMAD, Hippo/YAP/TAZ, and Wnt/β-catenin signaling in melanoma phenotype switching
por: Lüönd, Fabiana, et al.
Publicado: (2021)

LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development
por: Lee, Da-Hye, et al.
Publicado: (2016)

Divergent Metabolomic Signatures of TGFβ2 and TNFα in the Induction of Retinal Epithelial-Mesenchymal Transition
por: Ng, Pei Qin, et al.
Publicado: (2023)

Giving AXL the axe: targeting AXL in human malignancy
por: Gay, Carl M, et al.
Publicado: (2017)

Immune Evasion Mechanism and AXL
por: Son, Hye-Youn, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_31o5trsk196hdqqus8fgcglkvu