Protein folding modulates the chemical reactivity of a Gram-positive adhesin

Gram-positive bacteria colonize mucosal tissues against large mechanical perturbations, such as coughing, which generate shear forces that exceed the ability of non-covalent bonds to remain attached. To overcome these challenges, the pathogen Streptococcus pyogenes utilizes the protein Cpa, a pilus...

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Detalles Bibliográficos
Autores principales: Alonso-Caballero, Alvaro, Echelman, Daniel J., Tapia-Rojo, Rafael, Haldar, Shubhasis, Eckels, Edward C., Fernandez, Julio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858226/
https://www.ncbi.nlm.nih.gov/pubmed/33257887
http://dx.doi.org/10.1038/s41557-020-00586-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858226/
https://www.ncbi.nlm.nih.gov/pubmed/33257887
http://dx.doi.org/10.1038/s41557-020-00586-x

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