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Protein folding modulates the chemical reactivity of a Gram-positive adhesin
Gram-positive bacteria colonize mucosal tissues against large mechanical perturbations, such as coughing, which generate shear forces that exceed the ability of non-covalent bonds to remain attached. To overcome these challenges, the pathogen Streptococcus pyogenes utilizes the protein Cpa, a pilus...
Autores principales: | Alonso-Caballero, Alvaro, Echelman, Daniel J., Tapia-Rojo, Rafael, Haldar, Shubhasis, Eckels, Edward C., Fernandez, Julio M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858226/ https://www.ncbi.nlm.nih.gov/pubmed/33257887 http://dx.doi.org/10.1038/s41557-020-00586-x |
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