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4-Hydroxyisoleucine Alleviates Macrophage-Related Chronic Inflammation and Metabolic Syndrome in Mice Fed a High-Fat Diet

In obesity, macrophages and other immune cells accumulate in organs affected by insulin, leading to chronic inflammation and insulin resistance. 4-Hydroxyisoleucine (4-HIL) is a non-protein amino acid found in fenugreek seeds. 4-HIL enhances insulin sensitivity, but its mechanism is still unclear. I...

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Detalles Bibliográficos
Autores principales:	Yang, Jiali, Ran, Yunhui, Yang, Yonghui, Song, Shuyi, Wu, Yahong, Qi, Yuanming, Gao, Yanfeng, Li, Guodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858251/ https://www.ncbi.nlm.nih.gov/pubmed/33551809 http://dx.doi.org/10.3389/fphar.2020.606514

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