Cargando…

4-Hydroxyisoleucine Alleviates Macrophage-Related Chronic Inflammation and Metabolic Syndrome in Mice Fed a High-Fat Diet

In obesity, macrophages and other immune cells accumulate in organs affected by insulin, leading to chronic inflammation and insulin resistance. 4-Hydroxyisoleucine (4-HIL) is a non-protein amino acid found in fenugreek seeds. 4-HIL enhances insulin sensitivity, but its mechanism is still unclear. I...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Jiali, Ran, Yunhui, Yang, Yonghui, Song, Shuyi, Wu, Yahong, Qi, Yuanming, Gao, Yanfeng, Li, Guodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858251/ https://www.ncbi.nlm.nih.gov/pubmed/33551809 http://dx.doi.org/10.3389/fphar.2020.606514

Ejemplares similares

4-Hydroxyisoleucine inhibits tumor growth by triggering endoplasmic reticulum stress and autophagy
por: Li, Peng, et al.
Publicado: (2022)

Polydextrose Alleviates Adipose Tissue Inflammation and Modulates the Gut Microbiota in High-Fat Diet-Fed Mice
por: Hu, Qiuyue, et al.
Publicado: (2022)

Avocado oil alleviates non-alcoholic fatty liver disease by improving mitochondrial function, oxidative stress and inflammation in rats fed a high fat–High fructose diet
por: García-Berumen, Claudia Isabel, et al.
Publicado: (2022)

Effect of Berberine on Atherosclerosis and Gut Microbiota Modulation and Their Correlation in High-Fat Diet-Fed ApoE−/− Mice
por: Wu, Min, et al.
Publicado: (2020)

Naoxintong Capsule Alternates Gut Microbiota and Prevents Hyperlipidemia in High-Fat-Diet Fed Rats
por: Lu, Yihang, et al.
Publicado: (2022)

Effects of Xylooligosaccharides on Lipid Metabolism, Inflammation, and Gut Microbiota in C57BL/6J Mice Fed a High-Fat Diet
por: Li, Fang, et al.
Publicado: (2021)

Gamma Oryzanol Alleviates High-Fat Diet-Induced Anxiety-Like Behaviors Through Downregulation of Dopamine and Inflammation in the Amygdala of Mice
por: Akter, Salina, et al.
Publicado: (2020)

Spirulina Lipids Alleviate Oxidative Stress and Inflammation in Mice Fed a High-Fat and High-Sucrose Diet
por: Yang, Yuhong, et al.
Publicado: (2020)

Glucosamine Ameliorates Symptoms of High-Fat Diet-Fed Mice by Reversing Imbalanced Gut Microbiota
por: Yuan, Xubing, et al.
Publicado: (2021)

Limonin, an AMPK Activator, Inhibits Hepatic Lipid Accumulation in High Fat Diet Fed Mice
por: Wang, Si-wei, et al.
Publicado: (2022)

Dose-Related Urinary Metabolic Alterations of a Combination of Quercetin and Resveratrol-Treated High-Fat Diet Fed Rats
por: Zhuang, Tongxi, et al.
Publicado: (2021)

4-Hydroxyisoleucine relieves inflammation through iRhom2-dependent pathway in co-cultured macrophages and adipocytes with LPS stimulation
por: Zhou, Cong, et al.
Publicado: (2020)

Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation
por: Wagner, Karen M., et al.
Publicado: (2021)

Amelioration of cognitive impairment using epigallocatechin-3-gallate in ovariectomized mice fed a high-fat diet involves remodeling with Prevotella and Bifidobacteriales
por: Qu, Yang, et al.
Publicado: (2023)

Safranal Alleviates Dextran Sulfate Sodium-Induced Colitis and Suppresses Macrophage-Mediated Inflammation
por: Lertnimitphun, Peeraphong, et al.
Publicado: (2019)

Potential benefits of metformin and pioglitazone combination therapy via gut microbiota and metabolites in high-fat diet-fed mice
por: Wang, Dongmei, et al.
Publicado: (2022)

Inulin ameliorates metabolic syndrome in high-fat diet-fed mice by regulating gut microbiota and bile acid excretion
por: Huang, Shaoxiong, et al.
Publicado: (2023)

Pistachio Consumption Alleviates Inflammation and Improves Gut Microbiota Composition in Mice Fed a High-Fat Diet
por: Terzo, Simona, et al.
Publicado: (2020)

Low-Dose Piperlongumine Rescues Impaired Function of Endothelial Progenitor Cells and Reduces Cerebral Ischemic Injury in High-Fat Diet-Fed Mice
por: Dong, Xiao-Hui, et al.
Publicado: (2021)

Targeting Mitochondrial ROS-Mediated Ferroptosis by Quercetin Alleviates High-Fat Diet-Induced Hepatic Lipotoxicity
por: Jiang, Jin-Jin, et al.
Publicado: (2022)

Isochlorogenic Acid C Alleviates High-Fat Diet-Induced Hyperlipemia by Promoting Cholesterol Reverse Transport
por: Zheng, Liuyi, et al.
Publicado: (2022)

Dietary supplement of Smilax china L. ethanol extract alleviates the lipid accumulation by activating AMPK pathways in high-fat diet fed mice
por: Yang, Licong, et al.
Publicado: (2019)

Neuroprotective efficacy of 4-Hydroxyisoleucine in experimentally induced intracerebral hemorrhage
por: Mehmood Siddiqui, Ehraz, et al.
Publicado: (2021)

Traditional Chinese Medicine Formula Kang Shuai Lao Pian Improves Obesity, Gut Dysbiosis, and Fecal Metabolic Disorders in High-Fat Diet-Fed Mice
por: Gong, Shuqing, et al.
Publicado: (2020)

CBD Alleviates Liver Injuries in Alcoholics With High-Fat High-Cholesterol Diet Through Regulating NLRP3 Inflammasome–Pyroptosis Pathway
por: Jiang, Xuye, et al.
Publicado: (2021)

Erythropoietin Inhibits Gluconeogenesis and Inflammation in the Liver and Improves Glucose Intolerance in High-Fat Diet-Fed Mice
por: Meng, Ran, et al.
Publicado: (2013)

Integrated Metagenomic and Metabolomic Analyses of the Effect of Astragalus Polysaccharides on Alleviating High-Fat Diet–Induced Metabolic Disorders
por: Hong, Ying, et al.
Publicado: (2020)

Asparagus cochinchinensis alleviates disturbances of lipid metabolism and gut microbiota in high-fat diet-induced obesity mice
por: Luo, Shiyue, et al.
Publicado: (2022)

Epigallocatechin gallate alleviates high-fat diet-induced hepatic lipotoxicity by targeting mitochondrial ROS-mediated ferroptosis
por: Ding, Shi-Bin, et al.
Publicado: (2023)

Exercise training is more effective than resveratrol supplementation on alleviation of inflammation in peritoneal macrophages of high fat diet mice
por: Park, Hee Geun, et al.
Publicado: (2014)

Shenling Baizhu Powder Alleviates TNBS-Induced Colitis in Rats by Improving Intestinal Epithelial Permeability and Inhibiting Inflammation Through the TLR5/MyD88/NF-κB Pathway
por: Rao, Kehan, et al.
Publicado: (2022)

Modulation of the Gut Microbiota and Liver Transcriptome by Red Yeast Rice and Monascus Pigment Fermented by Purple Monascus SHM1105 in Rats Fed with a High-Fat Diet
por: Yang, Hua, et al.
Publicado: (2021)

Kun-Dan Decoction Ameliorates Insulin Resistance by Activating AMPK/mTOR-Mediated Autophagy in High-Fat Diet-Fed Rats
por: Su, Zuqing, et al.
Publicado: (2021)

Losartan Alleviates Renal Fibrosis and Inhibits Endothelial-to-Mesenchymal Transition (EMT) Under High-Fat Diet-Induced Hyperglycemia
por: Yao, Yufeng, et al.
Publicado: (2018)

Creosote Bush (Larrea tridentata) Improves Insulin Sensitivity and Reduces Plasma and Hepatic Lipids in Hamsters Fed a High Fat and Cholesterol Diet
por: Del Vecchyo-Tenorio, Georgina, et al.
Publicado: (2016)

Pterostilbene Alleviates Cholestasis by Promoting SIRT1 Activity in Hepatocytes and Macrophages
por: Ma, Chuanrui, et al.
Publicado: (2021)

Fermented Rosa Roxburghii Tratt Juice Alleviates High-Fat Diet-Induced Hyperlipidemia in Rats by Modulating Gut Microbiota and Metabolites
por: Ji, Jiacheng, et al.
Publicado: (2022)

Hepatocyte growth factor alleviates hepatic insulin resistance and lipid accumulation in high‐fat diet‐fed mice
por: Jing, Yali, et al.
Publicado: (2018)

Wild Blueberries (Vaccinium myrtillus) Alleviate Inflammation and Hypertension Associated with Developing Obesity in Mice Fed with a High-Fat Diet
por: Mykkänen, Otto T., et al.
Publicado: (2014)

Spirulina platensis alleviates chronic inflammation with modulation of gut microbiota and intestinal permeability in rats fed a high‐fat diet
por: Yu, Ting, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7n14phkqc5qs8j1m3f1vgj36eh