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Nanoparticle-Mediated Delivery of Emodin via Colonic Irrigation Attenuates Renal Injury in 5/6 Nephrectomized Rats

Our previous study showed that emodin enema modulates gut microbiota and delays CKD progression. However, the poor solubility, limited colonic irrigation retention time, and inadequate colon adhesion of emodin hinder its clinical application. Based on the deficiencies of emodin, we prepared monometh...

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Detalles Bibliográficos
Autores principales:	Lu, Zhaoyu, Ji, Chunlan, Luo, Xuewen, Lan, Yong, Han, Lijuan, Chen, Yang, Liu, Xusheng, Lin, Qinzhan, Lu, Fuhua, Wu, Xiuqing, Guo, Rui, Zou, Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858270/ https://www.ncbi.nlm.nih.gov/pubmed/33551808 http://dx.doi.org/10.3389/fphar.2020.606227

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