Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP)

The Plasmodium falciparum M1 alanyl aminopeptidase and M17 leucyl aminopeptidase, PfM1AAP and PfM17LAP, are potential targets for novel anti-malarial drug development. Inhibitors of these aminopeptidases have been shown to kill malaria parasites in culture and reduce parasite growth in murine models...

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Detalles Bibliográficos
Autores principales: Mathew, Rency, Wunderlich, Juliane, Thivierge, Karine, Cwiklinski, Krystyna, Dumont, Claire, Tilley, Leann, Rohrbach, Petra, Dalton, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858622/
https://www.ncbi.nlm.nih.gov/pubmed/33536500
http://dx.doi.org/10.1038/s41598-021-82499-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858622/
https://www.ncbi.nlm.nih.gov/pubmed/33536500
http://dx.doi.org/10.1038/s41598-021-82499-4

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