TSPAN5 influences serotonin and kynurenine: pharmacogenomic mechanisms related to alcohol use disorder and acamprosate treatment response

We previously reported that SNPs near TSPAN5 were associated with plasma serotonin (5-HT) concentrations which were themselves associated with selective serotonin reuptake inhibitor treatment outcomes in patients with major depressive disorder (MDD). TSPAN5 SNPs were also associated with alcohol con...

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Detalles Bibliográficos
Autores principales: Ho, Ming-Fen, Zhang, Cheng, Zhang, Lingxin, Wei, Lixuan, Zhou, Ying, Moon, Irene, Geske, Jennifer R., Choi, Doo-Sup, Biernacka, Joanna, Frye, Mark, Wen, Zhexing, Karpyak, Victor M., Li, Hu, Weinshilboum, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858703/
https://www.ncbi.nlm.nih.gov/pubmed/32753686
http://dx.doi.org/10.1038/s41380-020-0855-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7858703/
https://www.ncbi.nlm.nih.gov/pubmed/32753686
http://dx.doi.org/10.1038/s41380-020-0855-9

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